TNFRSF10B 抗体
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- 抗原 See all TNFRSF10B 抗体
- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNFRSF10B antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 特异性
- Human DR5
- 产品特性
- Rabbit Anti-Human DR5-UNLB
- 纯化方法
- Purified
- 免疫原
- Recombinant DR5
- 亚型
- IgG
- Top Product
- Discover our top product TNFRSF10B Primary Antibody
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- 应用备注
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- Applications: FC - Quality tested WB , ICC
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L Immunoblotting Purified (UNLB) antibody 2 g/mL Immunocytochemistry Purified (UNLB) antibody 2 g/mL
- 说明
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induction of apoptosis
- 样本量
- 0,2 mL
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- 0.1 mg of purified immunoglobulin in 0.2 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
- 储存液
- Without preservative
- 注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C
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- 抗原
- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
- 别名
- DR5 (TNFRSF10B 产品)
- 别名
- TNFRSF10B antibody, dr5 antibody, cd262 antibody, killer antibody, trick2 antibody, trickb antibody, xDR-M1 antibody, xDR-M2 antibody, ztnfr9 antibody, trailr2 antibody, trick2a antibody, trick2b antibody, CD262 antibody, DR5 antibody, KILLER antibody, KILLER/DR5 antibody, TRAIL-R2 antibody, TRAILR2 antibody, TRICK2 antibody, TRICK2A antibody, TRICK2B antibody, TRICKB antibody, ZTNFR9 antibody, Ly98 antibody, MK antibody, tumor necrosis factor receptor superfamily, member 10b antibody, tumor necrosis factor receptor superfamily member 10b S homeolog antibody, tumor necrosis factor receptor superfamily member 10b L homeolog antibody, tumor necrosis factor receptor superfamily member 10b antibody, TNF receptor superfamily member 10b antibody, Tnfrsf10b antibody, TNFRSF10B antibody, tnfrsf10b.S antibody, tnfrsf10b.L antibody, tnfrsf10b antibody
- 背景
- DR5, also known as TRAIL-R2, TRICK2 and KILLER, is a widely expressed type I membrane member of the tumor necrosis (TNF) receptor family. Members of this family contain multiple cysteine-rich repeats in their extracellular domain and while the cytoplasmic region is less conserved, they do contain an intracellular 80 AA motif known as the ‘death domain' (DD). DR5 is a receptor for the cytotoxic ligand TRAIL which induces apoptosis and it is the cytoplasmic DD that is responsible for transducing the death process. DR5 has also been shown to activate NF- λB.
- 途径
- p53 Pathway, Apoptosis, Positive Regulation of Endopeptidase Activity
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