TNFRSF10B 抗体 (AA 56-210)
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北京 101111
Quick Overview for TNFRSF10B 抗体 (AA 56-210) (ABIN7193299)
抗原
See all TNFRSF10B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 56-210
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原理
- TNFRSF10B Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human TNFRSF10B (AA: 56-210) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
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别名
- TNFRSF10B
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背景
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The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
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分子量
- 47.9 kDa
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基因ID
- 8795
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UniProt
- O14763
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途径
- p53 Pathway, Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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