TNFRSF10B 抗体 (AA 301-381)
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北京 101111
Quick Overview for TNFRSF10B 抗体 (AA 301-381) (ABIN733118)
抗原
See all TNFRSF10B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-381
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交叉反应
- 人
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预测反应
- Mouse,Rat
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from mouse DR5
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Dihydroartemisinin enhances Apo2L/TRAIL-mediated apoptosis in pancreatic cancer cells via ROS-mediated up-regulation of death receptor 5." in: PLoS ONE, Vol. 7, Issue 5, pp. e37222, (2012) (PubMed).
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: "Dihydroartemisinin enhances Apo2L/TRAIL-mediated apoptosis in pancreatic cancer cells via ROS-mediated up-regulation of death receptor 5." in: PLoS ONE, Vol. 7, Issue 5, pp. e37222, (2012) (PubMed).
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- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
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别名
- TRAILR2/DR5/CD262
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背景
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Synonyms: MK, DR5, Ly98, KILLER, TRICKB, TRAILR2, TRICK2A, TRICK2B, Tumor necrosis factor receptor superfamily member 10B, Death receptor 5, CD262, Tnfrsf10b
Background: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis (By similarity).
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基因ID
- 21933
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UniProt
- Q9QZM4
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途径
- p53 Pathway, Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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