TNFRSF10B 抗体 (N-Term)
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北京 101111
Quick Overview for TNFRSF10B 抗体 (N-Term) (ABIN6265635)
抗原
See all TNFRSF10B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- DR5 Antibody detects endogenous levels of total DR5.
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human DR5, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 234-435) antibody
TNFRSF10B 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) antibodyTNFRSF10B 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 233-440) antibodyTNFRSF10B 适用: 人, 小鼠, 大鼠 WB, FACS, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 1-440) antibodyTNFRSF10B 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 71-170) antibodyTNFRSF10B 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2D6 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 266-393) antibodyTNFRSF10B 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal DR5-3381 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-210) antibodyTNFRSF10B 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2H5B8 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 301-381) antibodyTNFRSF10B 适用: 人 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-210) antibodyTNFRSF10B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) antibodyTNFRSF10B 适用: 人, 小鼠 WB, ICC 宿主: 小鼠 Monoclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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: "Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells." in: Oncology letters, Vol. 15, Issue 1, pp. 483-488, (2018) (PubMed).
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: "Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells." in: Oncology letters, Vol. 15, Issue 1, pp. 483-488, (2018) (PubMed).
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- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
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别名
- TNFRSF10B
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背景
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Description: Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:10549288). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
Gene: TNFRSF10B
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分子量
- 48kDa
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基因ID
- 8795
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UniProt
- O14763
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途径
- p53 Pathway, Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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