TNFRSF10B 抗体 (AA 56-210)
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北京 101111
Quick Overview for TNFRSF10B 抗体 (AA 56-210) (ABIN3021808)
抗原
See all TNFRSF10B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 56-210
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序列
- ITQQDLAPQQ RAAPQQKRSS PSEGLCPPGH HISEDGRDCI SCKYGQDYST HWNDLLFCLR CTRCDSGEVE LSPCTTTRNT VCQCEEGTFR EEDSPEMCRK CRTGCPRGMV KVGDCTPWSD IECVHKESGT KHSGEVPAVE ETVTSSPGTP ASPCS
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 56-210 of human DR5/TRAILR2/TNFRSF10B (NP_003833.4).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
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别名
- TNFRSF10B
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背景
- The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.,CD262,DR5,KILLER,KILLER/DR5,TRAIL-R2,TRAILR2,TRICK2,TRICK2A,TRICK2B,TRICKB,ZTNFR9,TNFRSF10B,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Growth factor,TNF,Death Receptor Signaling Pathway,Immunology & Inflammation,CD markers,NF-kB Signaling Pathway,TNFRSF10B
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分子量
- 12 kDa/45 kDa/47 kDa
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基因ID
- 8795
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UniProt
- O14763
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途径
- p53 Pathway, Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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