TNFRSF10B 产品
(Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
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The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009].
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Featured TNFRSF10B Categories
TNFRSF10B 抗体
High quality antibodies with extensive validation data.
TNFRSF10B ELISA试剂盒
Reliable ELISA kits for a wide range of species.
TNFRSF10B 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TNFRSF10B 抗体
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Cat. No.
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Recommended TNFRSF10B ELISA试剂盒
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Recommended TNFRSF10B 蛋白
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Latest Publications for our TNFRSF10B Products
: "HIF-1α Mediates TRAIL-Induced Neuronal Apoptosis via Regulating DcR1 Expression Following Traumatic Brain Injury." in: Frontiers in cellular neuroscience, Vol. 14, pp. 192, (2020) (PubMed).: "LY3009120, a pan-Raf kinase inhibitor, inhibits adipogenesis of 3T3-L1 cells by controlling the expression and phosphorylation of C/EBP-α, PPAR-γ, STAT‑3, FAS, ACC, perilipin A, and AMPK." in: International journal of molecular medicine, Vol. 42, Issue 6, pp. 3477-3484, (2019) (PubMed).
: "Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells." in: Oncology letters, Vol. 15, Issue 1, pp. 483-488, (2018) (PubMed).
: "Meridianin C inhibits the growth of YD-10B human tongue cancer cells through macropinocytosis and the down-regulation of Dickkopf-related protein-3." in: Journal of cellular and molecular medicine, Vol. 22, Issue 12, pp. 5833-5846, (2018) (PubMed).
: "High-efficiency antibody discovery achieved with multiplexed microscopy." in: Microscopy (Oxford, England), Vol. 65, Issue 4, pp. 341-52, (2018) (PubMed).
: "Targeting scFv-Fc-scTRAIL fusion proteins to tumor cells." in: Oncotarget, Vol. 9, Issue 13, pp. 11322-11335, (2018) (PubMed).
: "Dual role of DR5 in death and survival signaling leads to TRAIL resistance in cancer cells." in: Cell death & disease, Vol. 8, Issue 8, pp. e3025, (2018) (PubMed).
: "Potential Role of CD133 Expression in the Susceptibility of Human Liver Cancer Stem-Like Cells to TRAIL." in: Oncology research, Vol. 24, Issue 6, pp. 495-509, (2017) (PubMed).
: "The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2." in: Molecular cell, Vol. 65, Issue 4, pp. 730-742.e5, (2017) (PubMed).
: "TNF-Related Apoptosis-Inducing Ligand (TRAIL)-Armed Exosomes Deliver Proapoptotic Signals to Tumor Site." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 14, pp. 3499-512, (2016) (PubMed).
Synonyms and alternative names related to TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b (Tnfrsf10b), tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), tumor necrosis factor receptor superfamily member 10b S homeolog (tnfrsf10b.S), tumor necrosis factor receptor superfamily member 10b L homeolog (tnfrsf10b.L), tumor necrosis factor receptor superfamily member 10b (tnfrsf10b), TNF receptor superfamily member 10b (TNFRSF10B), cd262, CD262, dr5, DR5, killer, KILLER, KILLER/DR5, Ly98, MK, TNFRSF10B, TRAIL-R2, trailr2, TRAILR2, trick2, TRICK2, trick2a, TRICK2A, trick2b, TRICK2B, trickb, TRICKB, xDR-M1, xDR-M2, ztnfr9, ZTNFR9Protein level used designations for TNFRSF10B
- tumor necrosis factor receptor superfamily, member 10b
- death receptor-M2
- death receptor-M1
- Fas-like protein
- TNF-related apoptosis-inducing ligand receptor 2
- apoptosis inducing protein TRICK2A/2B
- apoptosis inducing receptor TRAIL-R2
- cytotoxic TRAIL receptor-2
- death domain containing receptor for TRAIL/Apo-2L
- death receptor 5
- p53-regulated DNA damage-inducible cell death receptor(killer)
- tumor necrosis factor receptor superfamily member 10B
- tumor necrosis factor receptor-like protein ZTNFR9
- KILLER/DR5 TRAIL death-inducing receptor
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