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TNFRSF10A 产品

(Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008].

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Featured TNFRSF10A Categories

TNFRSF10A 抗体

High quality antibodies with extensive validation data.

TNFRSF10A ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TNFRSF10A 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TNFRSF10A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application FACS, IP, ICC
Validations
  • (1)
  • (2)
Cat. No. ABIN2749053
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN6149301
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN6149302
Quantity 100 μL
Datasheet Datasheet

Recommended TNFRSF10A ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970966
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960277
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN625358
Quantity 96 tests
Datasheet Datasheet

Recommended TNFRSF10A 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN7275778
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275776
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275777
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TNFRSF10A Products

Lee, Quan, Byun, Park, Kang, Piao, Ju, Ro, Na, Hur: "Accelerated degradation of cFLIPL and sensitization of the TRAIL DISC-mediated apoptotic cascade by pinoresinol, a lignan isolated from Rubia philippinensis." in: Scientific reports, Vol. 9, Issue 1, pp. 13505, (2019) (PubMed).

Mettler Izquierdo, Varela, Park, Collarini, Lu, Pramanick, Rucker, Lopalco, Etches, Harriman: "High-efficiency antibody discovery achieved with multiplexed microscopy." in: Microscopy (Oxford, England), Vol. 65, Issue 4, pp. 341-52, (2018) (PubMed).

Wen, Wang, Luo, Chu, Chen, Xu, Zang, Alnemah, Ma, Fan: "CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway." in: Oncotarget, Vol. 7, Issue 19, pp. 27787-801, (2016) (PubMed).

Foster, Jane, Premkumar, Morales, Pollack: "NVP-BKM120 potentiates apoptosis in tumor necrosis factor-related apoptosis-inducing ligand-resistant glioma cell lines via upregulation of Noxa and death receptor 5." in: International journal of oncology, Vol. 47, Issue 2, pp. 506-16, (2015) (PubMed).

Warat, Sadowski, Szliszka, Król, Czuba: "The role of selected flavonols in tumor necrosis factor-related apoptosis-inducing ligand receptor-1 (TRAIL-R1) expression on activated RAW 264.7 macrophages." in: Molecules (Basel, Switzerland), Vol. 20, Issue 1, pp. 900-12, (2015) (PubMed).

Kang, Goldstein, Yu, Meltzer, Loeb, Cao: "Caspase-8 expression is predictive of tumour response to death receptor 5 agonist antibody in Ewing's sarcoma." in: British journal of cancer, Vol. 113, Issue 6, pp. 894-901, (2015) (PubMed).

Liu, Zuo, Wang, Chen, Yang, Wang, Zhu: "miR-942 decreases TRAIL-induced apoptosis through ISG12a downregulation and is regulated by AKT." in: Oncotarget, Vol. 5, Issue 13, pp. 4959-71, (2014) (PubMed).

Neumann, Hasenauer, Pollak, Scheurich: "Dominant negative effects of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 4 on TRAIL receptor 1 signaling by formation of heteromeric complexes." in: The Journal of biological chemistry, Vol. 289, Issue 23, pp. 16576-87, (2014) (PubMed).

Kim, Woo, Jeong, Ryu, Jang, Jeun: "Potential application of temozolomide in mesenchymal stem cell-based TRAIL gene therapy against malignant glioma." in: Stem cells translational medicine, Vol. 3, Issue 2, pp. 172-82, (2014) (PubMed).

Cosgrove, Ussher, Rauch, Gärtner, Kurioka, Hühn, Adelmann, Kang, Fergusson, Simmonds, Goulder, Hansen, Fox, Günthard, Khanna, Powrie, Steel, Gazzard, Phillips, Frater, Uhlig, Klenerman: "Early and nonreversible decrease of CD161++ /MAIT cells in HIV infection." in: Blood, Vol. 121, Issue 6, pp. 951-61, (2013) (PubMed).

Synonyms and alternative names related to TNFRSF10A

TNF receptor superfamily member 10a (TNFRSF10A), tumor necrosis factor receptor superfamily member 26 (LOC510798), tumor necrosis factor receptor superfamily, member 10a (TNFRSF10A), APO2, CD261, DR4, TNFRSF10A, TRAILR-1, TRAILR1

Protein level used designations for TNFRSF10A

  • TNF-related apoptosis-inducing ligand receptor 1
  • TRAIL receptor 1
  • TRAIL-R1
  • cytotoxic TRAIL receptor
  • death receptor 4
  • tumor necrosis factor receptor superfamily member 10A
  • tumor necrosis factor receptor superfamily member 10a variant 2
  • tumor necrosis factor receptor superfamily, member 10a
  • tumor necrosis factor receptor superfamily member 10A-like
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