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TNF alpha (Infliximab Biosimilar) 抗体

(TNF alpha (Infliximab Biosimilar))
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008].

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Recommended TNF alpha (Infliximab Biosimilar) 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application FACS, ELISA, in vivo
Validations
  • (1)
Cat. No. ABIN5668147
Quantity 200 μg
Datasheet Datasheet
Reactivity Human
Application FACS, in vivo
Validations
Cat. No. ABIN7200661
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Application FACS, ELISA, in vivo
Validations
Cat. No. ABIN5668148
Quantity 200 μg
Datasheet Datasheet

Latest Publications for our TNF alpha (Infliximab Biosimilar) Products

Farkas, Rutka, Golovics, Végh, Lovász, Nyári, Gecse, Kolar, Bortlik, Duricova, Machkova, Hruba, Lukas, Mitrova, Malickova, Bálint, Nagy, Bor, Milassin, Szepes, Palatka, Lakatos, Lukas, Molnár: "Efficacy of Infliximab Biosimilar CT-P13 Induction Therapy on Mucosal Healing in Ulcerative Colitis." in: Journal of Crohn's & colitis, Vol. 10, Issue 11, pp. 1273-1278, (2017) (PubMed).

Bálint, Rutka, Végh, Kürti, Gecse, Banai, Bene, Gasztonyi, Kristóf, Lakatos, Miheller, Palatka, Patai, Salamon, Szamosi, Szepes, Tóth, Vincze, Bor, Milassin, Fábián, Nagy, Kolar, Bortlik, Duricova et al.: "Frequency and characteristics of infusion reactions during biosimilar infliximab treatment in inflammatory bowel diseases: results from Central European nationwide cohort. ..." in: Expert opinion on drug safety, Vol. 16, Issue 8, pp. 885-890, (2017) (PubMed).

Synonyms and alternative names related to TNF alpha (Infliximab Biosimilar)

tumor necrosis factor (TNF), DIF, TNF-alpha, TNFA, TNFSF2

Protein level used designations for TNF alpha (Infliximab Biosimilar)

  • APC1 protein
  • TNF, macrophage-derived
  • TNF, monocyte-derived
  • TNF-a
  • cachectin
  • tumor necrosis factor ligand superfamily member 2
  • tumor necrosis factor-alpha
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