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TNFRSF13C 产品

(Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))

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B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008].

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Featured TNFRSF13C Categories

TNFRSF13C 抗体

High quality antibodies with extensive validation data.

TNFRSF13C ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TNFRSF13C 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TNFRSF13C 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, ELISA, FACS, IHC, ICC, Neut
Validations
  • (5)
Cat. No. ABIN5611148
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS, IHC, ICC, Neut
Validations
  • (4)
Cat. No. ABIN5611147
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS
Validations
  • (2)
Cat. No. ABIN7092943
Quantity 100 μg
Datasheet Datasheet

Recommended TNFRSF13C ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6960290
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970978
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1706072
Quantity 96 tests
Datasheet Datasheet

Recommended TNFRSF13C 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN7273910
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN7273915
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7273912
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TNFRSF13C Products

de Vos, Guel, Niebel, Bald, Ter Steege, Bieber, Wenzel: "Characterization of B cells in lupus erythematosus skin biopsies in the context of different immune cell infiltration patterns." in: Frontiers in medicine, Vol. 9, pp. 1037408, (2022) (PubMed).

Egia-Mendikute, Arpa, Rosell-Mases, Corral-Pujol, Carrascal, Carrillo, Mora, Chapman, Panosa, Vives-Pi, Stratmann, Serreze, Verdaguer: "B-Lymphocyte Phenotype Determines T-Lymphocyte Subset Differentiation in Autoimmune Diabetes." in: Frontiers in immunology, Vol. 10, pp. 1732, (2019) (PubMed).

Ma, Zhang, Liu, Wang, Liu, Zhu, Yu, Han, Chen, Hou, Wang, Ma, Shen, Li, Xiao, Wang: "B cell activating factor (BAFF) selects IL-10(-)B cells over IL-10(+)B cells during inflammatory responses." in: Molecular immunology, Vol. 85, pp. 18-26, (2017) (PubMed).

Saulep-Easton, Vincent, Quah, Wei, Ting, Croce, Tam, Mackay: "The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells." in: Leukemia, Vol. 30, Issue 1, pp. 163-72, (2016) (PubMed).

Maddur, Sharma, Hegde, Stephen-Victor, Pulendran, Kaveri, Bayry: "Human B cells induce dendritic cell maturation and favour Th2 polarization by inducing OX-40 ligand." in: Nature communications, Vol. 5, pp. 4092, (2014) (PubMed).

Deng, Zhang, Wang, Xu, Zhang, Yang, Mao, Gao, Song, Kong, Qu: "Soluble BAFF-R produced by decidual stromal cells plays an inhibitory role in monocytes and macrophages." in: Reproductive biomedicine online, Vol. 24, Issue 6, pp. 654-63, (2012) (PubMed).

Tussiwand, Rauch, Flück, Rolink: "BAFF-R expression correlates with positive selection of immature B cells." in: European journal of immunology, Vol. 42, Issue 1, pp. 206-16, (2012) (PubMed).

Notas, Alexaki, Kampa, Pelekanou, Charalampopoulos, Sabour-Alaoui, Pediaditakis, Dessirier, Gravanis, Stathopoulos, Tsapis, Castanas: "APRIL binding to BCMA activates a JNK2-FOXO3-GADD45 pathway and induces a G2/M cell growth arrest in liver cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 10, pp. 4748-58, (2012) (PubMed).

Ohmatsu, Sugaya, Miyagaki, Suga, Fujita, Asano, Tada, Kadono, Sato: "BAFF levels are increased in lesional skin and sera in patients with cutaneous T-cell lymphoma." in: The British journal of dermatology, Vol. 167, Issue 2, pp. 359-67, (2012) (PubMed).

Luster, Mukherjee, Carrell, Cho, Gill, Kelly, Garcia, Ward, Oh, Ullrich, Migone, Humphreys: "Fusion toxin BLyS-gelonin inhibits growth of malignant human B cell lines in vitro and in vivo." in: PLoS ONE, Vol. 7, Issue 10, pp. e47361, (2012) (PubMed).

Synonyms and alternative names related to TNFRSF13C

TNF receptor superfamily member 13C (TNFRSF13C), TNF receptor superfamily member 13C (Tnfrsf13c), uncharacterized LOC746611 (LOC746611), tumor necrosis factor receptor superfamily, member 13c (Tnfrsf13c), 2010006P15Rik, BAFF-R, BAFFR, Baffr, Bcmd, Bcmd-1, Bcmd1, BROMIX, CD268, CVID4, Lvis22, prolixin, RGD1560810, TNFRSF13C

Protein level used designations for TNFRSF13C

  • tumor necrosis factor receptor superfamily, member 13C
  • tumor necrosis factor receptor superfamily member 13C
  • B cell-activating factor receptor
  • B-cell-activating factor receptor
  • BAFF receptor
  • BLyS receptor 3
  • B-cell maturation defect 1
  • b cell-activating factor receptor
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