TNFSF15 产品
(Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
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The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].
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Featured TNFSF15 Categories
TNFSF15 抗体
High quality antibodies with extensive validation data.
TNFSF15 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
TNFSF15 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TNFSF15 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (1)
- (4)
Cat. No.
ABIN709556
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, StM
Validations
- (5)
Cat. No.
ABIN6941291
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC, StM
Validations
- (4)
Cat. No.
ABIN6941290
Quantity
100 μg
Datasheet
Datasheet
Recommended TNFSF15 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970946
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960752
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6974123
Quantity
96 tests
Datasheet
Datasheet
Recommended TNFSF15 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274680
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274686
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
Cat. No.
ABIN5510055
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our TNFSF15 Products
: "T cell expression of IL-18R and DR3 is essential for non-cognate stimulation of Th1 cells and optimal clearance of intracellular bacteria." in: PLoS pathogens, Vol. 13, Issue 8, pp. e1006566, (2017) (PubMed).: "TL1A as a potential local inducer of IL17A Expression in colon mucosa of inflammatory bowel disease patients." in: Scandinavian journal of immunology, (2015) (PubMed).
: "Tumour necrosis factor superfamily member 15 (Tnfsf15) facilitates lymphangiogenesis via up-regulation of Vegfr3 gene expression in lymphatic endothelial cells." in: The Journal of pathology, Vol. 237, Issue 3, pp. 307-18, (2015) (PubMed).
: "S100A9: A Potential Biomarker for the Progression of Non-Alcoholic Fatty Liver Disease and the Diagnosis of Non-Alcoholic Steatohepatitis." in: PLoS ONE, Vol. 10, Issue 5, pp. e0127352, (2015) (PubMed).
: "Cloning, expression, and functional characterization of TL1A-Ig." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 4, pp. 1540-50, (2013) (PubMed).
: "TL1A-induced NF-kappaB activation and c-IAP2 production prevent DR3-mediated apoptosis in TF-1 cells." in: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 39251-8, (2003) (PubMed).
: "Expression, localization, and functional activity of TL1A, a novel Th1-polarizing cytokine in inflammatory bowel disease." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 9, pp. 4868-74, (2003) (PubMed).
: "Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis." in: Science (New York, N.Y.), Vol. 293, Issue 5536, pp. 1829-32, (2001) (PubMed).
: "Apoptosis. Till death us do part." in: Science (New York, N.Y.), Vol. 293, Issue 5536, pp. 1784-5, (2001) (PubMed).
: "TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95)." in: Immunity, Vol. 6, Issue 1, pp. 79-88, (1997) (PubMed).
Synonyms and alternative names related to TNFSF15
tumor necrosis factor superfamily member 15 (TNFSF15), TNF superfamily member 15 (TNFSF15), tumor necrosis factor (ligand) superfamily, member 15 (Tnfsf15), TNF superfamily member 15 (Tnfsf15), TL1, Tl1, TL1A, Tl1a, TTPAL, VEGI, Vegi, VEGI192AProtein level used designations for TNFSF15
- tumor necrosis factor ligand superfamily member 15
- vascular endothelial growth inhibitor
- tocopherol (alpha) transfer protein-like
- TNF ligand-related molecule 1
- TNF superfamily ligand TL1A
- vascular endothelial cell growth inhibitor
- vascular endothelial growth inhibitor-192A
- bM20K13.3 (tumor necrosis factor (ligand) superfamily, member 15)
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