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TNNI2 产品

(Fast Skeletal Troponin I (TNNI2))

Categories

This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009].

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Featured TNNI2 Categories

TNNI2 抗体

High quality antibodies with extensive validation data.

TNNI2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TNNI2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TNNI2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (2)
  • (7)
Cat. No. ABIN969441
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, ICC, FACS
Validations
  • (2)
  • (5)
Cat. No. ABIN969572
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC, IF
Validations
  • (4)
Cat. No. ABIN7076031
Quantity 100 μL
Datasheet Datasheet

Recommended TNNI2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970876
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960189
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960190
Quantity 96 tests
Datasheet Datasheet

Recommended TNNI2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323281
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323279
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3074620
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TNNI2 Products

Fan, Long, Yan, Wang, Shi, Bao, Hu, Li, Chen, Zheng, Yan: "Dietary leucine supplementation alters energy metabolism and induces slow-to-fast transitions in longissimus dorsi muscle of weanling piglets." in: The British journal of nutrition, Vol. 117, Issue 9, pp. 1222-1234, (2017) (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

Wang, Luo, Sun, Deng, Li, Tao, Hu, Gong: "[Inhibitory effect of N-terminal 24 amino acids of the p55 gamma, a regulatory subunit of phosphoinositide 3-kinase, on proliferation of colon carcinoma cell line HT29]." in: Ai zheng = Aizheng = Chinese journal of cancer, Vol. 27, Issue 10, pp. 1034-8, (2008) (PubMed).

Moran, Garriock, Miller, Heimark, Gregorio, Krieg: "Expression of the fast twitch troponin complex, fTnT, fTnI and fTnC, in vascular smooth muscle." in: Cell motility and the cytoskeleton, Vol. 65, Issue 8, pp. 652-61, (2008) (PubMed).

Synonyms and alternative names related to TNNI2

troponin I2, fast skeletal type (TNNI2), troponin I type 2 (skeletal, fast) (TNNI2), troponin I2, fast skeletal type (Tnni2), troponin I, fast skeletal muscle-like (TNNI2), troponin I, skeletal, fast 2 (Tnni2), troponin I type 2a (skeletal, fast), tandem duplicate 4 (tnni2a.4), AMCD2B, DA2B, FSSV, fsTnI, hm:zehn0173, TnI, TNI, TnI-F4, tnni2, tropI-1d, zgc:86800

Protein level used designations for TNNI2

  • fast-twitch skeletal muscle troponin I
  • troponin I fast twitch 2
  • troponin I, fast skeletal muscle
  • troponin I, fast-twitch isoform
  • troponin I, fast-twitch skeletal muscle isoform
  • troponin I, skeletal, fast
  • troponin I fast-twitch skeletal isoform
  • troponin 1, type 2
  • troponin I, skeletal, fast 2
  • sTnI protein (aa 85-182)
  • fast muscle troponin I
  • troponin I type 2 (skeletal, fast)
  • troponin I, skeletal, fast 2a.4
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