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TNNI1 产品

(Slow Skeletal Troponin I (TNNI1))
Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit\; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. [provided by RefSeq, Jul 2008].

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Featured TNNI1 Categories

TNNI1 抗体

High quality antibodies with extensive validation data.

TNNI1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TNNI1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TNNI1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7435427
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (1)
  • (4)
Cat. No. ABIN2777151
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7435424
Quantity 100 μL
Datasheet Datasheet

Recommended TNNI1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6960188
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970874
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960187
Quantity 96 tests
Datasheet Datasheet

Recommended TNNI1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125117
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323277
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3074747
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TNNI1 Products

Fan, Long, Yan, Wang, Shi, Bao, Hu, Li, Chen, Zheng, Yan: "Dietary leucine supplementation alters energy metabolism and induces slow-to-fast transitions in longissimus dorsi muscle of weanling piglets." in: The British journal of nutrition, Vol. 117, Issue 9, pp. 1222-1234, (2017) (PubMed).

Park, Choi, Jung, Yu, Ryu, Kim, Jo, Choi, Jung: "Myogenic differentiation potential of human tonsil-derived mesenchymal stem cells and their potential for use to promote skeletal muscle regeneration." in: International journal of molecular medicine, Vol. 37, Issue 5, pp. 1209-20, (2016) (PubMed).

Salzler, Shah, Doré, Bauerlein, Miloscio, Latres, Papadopoulos, Olson, MacDonald, Duan: "Myostatin deficiency but not anti-myostatin blockade induces marked proteomic changes in mouse skeletal muscle." in: Proteomics, Vol. 16, Issue 14, pp. 2019-27, (2016) (PubMed).

Ma, Zheng, Hu, Wang, Yang, Jiang: "Dietary L-arginine supplementation affects the skeletal longissimus muscle proteome in finishing pigs." in: PLoS ONE, Vol. 10, Issue 1, pp. e0117294, (2015) (PubMed).

Vyatchin, Shevchenko, Lazarev, Matusovsky, Sheludko: "Troponin-like regulation in muscle thin filaments of the mussel Crenomytilus grayanus (Bivalvia: Mytiloida)." in: Biochimica et biophysica acta, Vol. 1854, Issue 10 Pt A, pp. 1444-50, (2015) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Chakraborty, Sengupta, Yutzey: "Tbx20 promotes cardiomyocyte proliferation and persistence of fetal characteristics in adult mouse hearts." in: Journal of molecular and cellular cardiology, Vol. 62, pp. 203-13, (2013) (PubMed).

Harmelink, Peng, DeBenedittis, Chen, Shou, Jiao: "Myocardial Mycn is essential for mouse ventricular wall morphogenesis." in: Developmental biology, Vol. 373, Issue 1, pp. 53-63, (2012) (PubMed).

Lichtenauer, Mildner, Hoetzenecker, Zimmermann, Podesser, Sipos, Berényi, Dworschak, Tschachler, Gyöngyösi, Ankersmit: "Secretome of apoptotic peripheral blood cells (APOSEC) confers cytoprotection to cardiomyocytes and inhibits tissue remodelling after acute myocardial infarction: a preclinical study." in: Basic research in cardiology, Vol. 106, Issue 6, pp. 1283-97, (2011) (PubMed).

Engel, Kobayashi, Biesiadecki, Davis, Tikunova, Wu, Solaro: "Identification of a region of troponin I important in signaling cross-bridge-dependent activation of cardiac myofilaments." in: The Journal of biological chemistry, Vol. 282, Issue 1, pp. 183-93, (2007) (PubMed).

Synonyms and alternative names related to TNNI1

troponin T1, slow skeletal type (TNNT1), troponin I1, slow skeletal type (TNNI1), troponin I, skeletal, slow 1 (Tnni1), troponin I1, slow skeletal type (Tnni1), troponin T1, skeletal, slow (Tnnt1), troponin T1, slow skeletal type (Tnnt1), troponin I1, slow skeletal type S homeolog (tnni1.S), troponin I type 1 (skeletal, slow) (TNNI1), troponin I4b, tandem duplicate 2 (tnni4b.2), 2700018B22Rik, AI747285, ANM, AW146156, Fang2, NEM5, SSTNI, ssTnI, ssTnT, STNT, sTnT, TnI-S4, TNN1, TNT, Tnt, TNTS, tnTs, troponin 1, zgc:86895

Protein level used designations for TNNI1

  • nemaline myopathy type 5
  • slow skeletal muscle troponin T
  • troponin T, slow skeletal muscle
  • troponin-T1, skeletal, slow
  • sTnT
  • tnTs
  • troponin T1, skeletal, slow
  • troponin T slow type isoform sTnT1
  • troponin I, slow skeletal muscle
  • troponin I, slow-twitch isoform
  • Troponin I, slow isoform
  • troponin I, skeletal, slow 1
  • skeletal muscle slow-twitch TnT
  • TnnI1
  • Troponin I, slow skeletal muscle
  • troponin I type 1 (skeletal, slow)
  • troponin I, skeletal, slow
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