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TNFRSF10B 抗体 (N-Term)

TNFRSF10B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792103
发货至: 中国
  • 抗原 See all TNFRSF10B 抗体
    TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
    抗原表位
    • 15
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    N-Term
    适用
    • 91
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    宿主
    • 60
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    • 1
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    克隆类型
    • 59
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    多克隆
    标记
    • 65
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    This TNFRSF10B antibody is un-conjugated
    应用范围
    • 70
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    • 29
    • 25
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    Western Blotting (WB)
    序列
    LVLVVAAVLL LVSAESALIT QQDLAPQQRA APQQKRSSPS EGLCPPGHHI
    预测反应
    Human: 100%
    产品特性
    This is a rabbit polyclonal antibody against TNFRSF10B. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human TNFRSF10B
    Top Product
    Discover our top product TNFRSF10B Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 440 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
    别名
    TNFRSF10B (TNFRSF10B 产品)
    别名
    TNFRSF10B antibody, dr5 antibody, cd262 antibody, killer antibody, trick2 antibody, trickb antibody, xDR-M1 antibody, xDR-M2 antibody, ztnfr9 antibody, trailr2 antibody, trick2a antibody, trick2b antibody, CD262 antibody, DR5 antibody, KILLER antibody, KILLER/DR5 antibody, TRAIL-R2 antibody, TRAILR2 antibody, TRICK2 antibody, TRICK2A antibody, TRICK2B antibody, TRICKB antibody, ZTNFR9 antibody, Ly98 antibody, MK antibody, tumor necrosis factor receptor superfamily, member 10b antibody, tumor necrosis factor receptor superfamily member 10b S homeolog antibody, tumor necrosis factor receptor superfamily member 10b L homeolog antibody, tumor necrosis factor receptor superfamily member 10b antibody, TNF receptor superfamily member 10b antibody, Tnfrsf10b antibody, TNFRSF10B antibody, tnfrsf10b.S antibody, tnfrsf10b.L antibody, tnfrsf10b antibody
    背景
    The protein is a member of the TNF-receptor superfamily, and contains an intracelluar death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracelluar death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.
    Alias Symbols: CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
    Protein Interaction Partner: TNFSF10, UBC, CFLAR, FADD, CUL3, TRAF2, CASP8, TNFRSF10A, RIPK1, TNFAIP3, ITCH, CBL, TNFRSF10D, MADD, TRADD, CASP10, TIMM50, EZR, TNFRSF1A, MAPK8, MSN, BID, ARHGDIA, RHOA, FASLG, FAS, TP53, RARA, PRKCD,
    Protein Size: 440
    分子量
    42 kDa
    基因ID
    8795
    NCBI登录号
    NM_003842, NP_003833
    UniProt
    O14763
    途径
    p53 Pathway, Apoptosis, Positive Regulation of Endopeptidase Activity
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