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CHEK1 抗体
CHEK1
适用: 人, 小鼠
WB, ELISA
宿主: 小鼠
Monoclonal
unconjugated
CHEK1抗体详情
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抗原
See all CHEK1 抗体
CHEK1
(Checkpoint Kinase 1 (CHEK1))
适用
All reactivities for CHEK1 抗体
人, 小鼠
宿主
All hosts for CHEK1 抗体
小鼠
克隆类型
All clonalities for CHEK1 抗体
单克隆
标记
All conjugates for CHEK1 抗体
This CHEK1 antibody is un-conjugated
应用范围
All applications for CHEK1 抗体
Western Blotting (WB), ELISA
纯化方法
Purified antibody
免疫原
Purified recombinant fragment of CHK1 expressed in E. coli.
亚型
IgG1
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Discover our top product CHEK1 Primary Antibody
Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1.0 mg/mL
缓冲液
PBS containing 0.03 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
CHEK1目标详情
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抗原
CHEK1
(Checkpoint Kinase 1 (CHEK1))
别名
CHK1 (CHEK1 产品 )
别名
An08g10320 antibody, AO090003000441 antibody, CHK1 antibody, chk1 antibody, C85740 antibody, Chk1 antibody, rad27 antibody, id:ibd2720 antibody, zgc:56093 antibody, CHEK1 antibody, checkpoint kinase 1 antibody, serine/threonine-protein kinase chk1 antibody, serine/threonine-protein kinase Chk1 antibody, CAMK/CAMKL/CHK1 protein kinase Chk1 antibody, checkpoint kinase 1 S homeolog antibody, CHEK1 antibody, ANI_1_2436074 antibody, AOR_1_768154 antibody, PTRG_04183 antibody, SJAG_01680 antibody, PAAG_04978 antibody, MCYG_03290 antibody, VDBG_03742 antibody, chek1.S antibody, Chek1 antibody, chek1 antibody
背景
CHK1, also known as CHEK1, it is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis.Cdc25, when phosphorylated on serine 216 by chk1 becomes bound by an adaptor protein in the cytoplasm.Therefore it is inhibited from removing the inhibiting phosphate from MPF (mitotic/maturation promoting factor) added by Wee1.Consequently, a cell is prevented from entering mitosis.Chk1 can also phosphorylate p53 at Ser20 in vitro.
分子量
56 kDa
基因ID
1111
途径
p53 Pathway , Apoptosis , Cell Division Cycle , DNA Damage Repair
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