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CHEK1 抗体

CHEK1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7263651
发货至: 中国
  • 抗原 See all CHEK1 抗体
    CHEK1 (Checkpoint Kinase 1 (CHEK1))
    适用
    • 212
    • 118
    • 67
    • 16
    • 9
    • 9
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 221
    • 14
    • 7
    • 5
    克隆类型
    • 209
    • 39
    多克隆
    标记
    • 132
    • 13
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    • 9
    • 9
    • 9
    • 9
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    • 8
    • 8
    • 5
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    • 4
    • 4
    • 4
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    This CHEK1 antibody is un-conjugated
    应用范围
    • 170
    • 87
    • 52
    • 41
    • 40
    • 36
    • 34
    • 17
    • 16
    • 13
    • 10
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    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide of human CHEK1
    亚型
    IgG
    Top Product
    Discover our top product CHEK1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CHEK1 (Checkpoint Kinase 1 (CHEK1))
    别名
    CHEK1 (CHEK1 产品)
    背景
    The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
    分子量

    Observed_MW: 54 kDa

    Calculated_MW: 43 kDa/50 kDa/54 kDa

    基因ID
    1111
    UniProt
    O14757
    途径
    p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
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