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TNFRSF10B 抗体 (AA 388-407)
TNFRSF10B
适用: 人, 小鼠
WB, ICC, IHC (p), IF
宿主: 兔
Polyclonal
unconjugated
TNFRSF10B抗体详情
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抗原
See all TNFRSF10B 抗体
TNFRSF10B
(Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
抗原表位
All epitopes for TNFRSF10B 抗体
AA 388-407
适用
All reactivities for TNFRSF10B 抗体
人, 小鼠
宿主
All hosts for TNFRSF10B 抗体
兔
克隆类型
All clonalities for TNFRSF10B 抗体
多克隆
标记
All conjugates for TNFRSF10B 抗体
This TNFRSF10B antibody is un-conjugated
应用范围
All applications for TNFRSF10B 抗体
Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
特异性
Reacts with human and mouse DR5.
纯化方法
Purified
免疫原
Synthetic peptide corresponding to aa 388- 407 of human DR5 precursor (accession no.AF012535)
亚型
IgG
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Discover our top product TNFRSF10B Primary Antibody
Alternatives
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使用细节
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应用备注
Working dilution: Optimal dilution should be determined by the end user. The following are guidelines only: WB(2 μg/mL) ICC(5 μg/mL)
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
PBS, pH 7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Dilute in PBS or medium which is identical to that used in the assay system.
储存条件
-20 °C
储存方法
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
TNFRSF10B目标详情
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抗原
TNFRSF10B
(Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
别名
DR5 (TNFRSF10B 产品 )
别名
TNFRSF10B antibody, dr5 antibody, cd262 antibody, killer antibody, trick2 antibody, trickb antibody, xDR-M1 antibody, xDR-M2 antibody, ztnfr9 antibody, trailr2 antibody, trick2a antibody, trick2b antibody, CD262 antibody, DR5 antibody, KILLER antibody, KILLER/DR5 antibody, TRAIL-R2 antibody, TRAILR2 antibody, TRICK2 antibody, TRICK2A antibody, TRICK2B antibody, TRICKB antibody, ZTNFR9 antibody, Ly98 antibody, MK antibody, tumor necrosis factor receptor superfamily, member 10b antibody, tumor necrosis factor receptor superfamily member 10b S homeolog antibody, tumor necrosis factor receptor superfamily member 10b L homeolog antibody, tumor necrosis factor receptor superfamily member 10b antibody, TNF receptor superfamily member 10b antibody, Tnfrsf10b antibody, TNFRSF10B antibody, tnfrsf10b.S antibody, tnfrsf10b.L antibody, tnfrsf10b antibody
背景
Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain-containing receptors. TRAIL/Apo2L is a new member of the TNF family. A novel death domain containing receptor for TRAIL was recently identified and designated DR5, Apo2, TRAIL-R2, TRICK2, or KILLER by several independent laboratories. Like DR4, DR5 transcript is widely expressed in normal tissues and in many types of tumor cells. DR5 binds to TRAIL and mediates TRAIL induced cell death. Overexpression of DR5 induces apoptosis and activates NF-kB. Tumor necrosis factor receptor superfamily member 10B Death receptor 5 TNF-related apoptosis-inducing ligand receptor 2, TRAIL receptor 2, TRAIL-R2 CD_antigen: CD262 KILLER/DR5,TRICK2A, TRICK2B, TRICKB Gene name: TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
基因ID
8795
UniProt
O14763
途径
p53 Pathway , Apoptosis , Positive Regulation of Endopeptidase Activity
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