电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

TNFRSF10B 抗体 (AA 388-407)

TNFRSF10B 适用: 人, 小鼠 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1733770
发货至: 中国
  • 抗原 See all TNFRSF10B 抗体
    TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
    抗原表位
    • 15
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 388-407
    适用
    • 96
    • 17
    • 4
    • 1
    • 1
    人, 小鼠
    宿主
    • 63
    • 37
    • 3
    • 1
    • 1
    • 1
    克隆类型
    • 60
    • 43
    • 2
    多克隆
    标记
    • 70
    • 10
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNFRSF10B antibody is un-conjugated
    应用范围
    • 73
    • 35
    • 29
    • 25
    • 16
    • 15
    • 15
    • 13
    • 11
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    Reacts with human and mouse DR5.
    纯化方法
    Purified
    免疫原
    Synthetic peptide corresponding to aa 388- 407 of human DR5 precursor (accession no.AF012535)
    亚型
    IgG
    Top Product
    Discover our top product TNFRSF10B Primary Antibody
  • 应用备注
    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only:
    WB(2 μg/mL) ICC(5 μg/mL)
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Dilute in PBS or medium which is identical to that used in the assay system.
    储存条件
    -20 °C
    储存方法
    This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
  • 抗原
    TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
    别名
    DR5 (TNFRSF10B 产品)
    别名
    TNFRSF10B antibody, dr5 antibody, cd262 antibody, killer antibody, trick2 antibody, trickb antibody, xDR-M1 antibody, xDR-M2 antibody, ztnfr9 antibody, trailr2 antibody, trick2a antibody, trick2b antibody, CD262 antibody, DR5 antibody, KILLER antibody, KILLER/DR5 antibody, TRAIL-R2 antibody, TRAILR2 antibody, TRICK2 antibody, TRICK2A antibody, TRICK2B antibody, TRICKB antibody, ZTNFR9 antibody, Ly98 antibody, MK antibody, tumor necrosis factor receptor superfamily, member 10b antibody, tumor necrosis factor receptor superfamily member 10b S homeolog antibody, tumor necrosis factor receptor superfamily member 10b L homeolog antibody, tumor necrosis factor receptor superfamily member 10b antibody, TNF receptor superfamily member 10b antibody, Tnfrsf10b antibody, TNFRSF10B antibody, tnfrsf10b.S antibody, tnfrsf10b.L antibody, tnfrsf10b antibody
    背景
    Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain-containing receptors. TRAIL/Apo2L is a new member of the TNF family. A novel death domain containing receptor for TRAIL was recently identified and designated DR5, Apo2, TRAIL-R2, TRICK2, or KILLER by several independent laboratories. Like DR4, DR5 transcript is widely expressed in normal tissues and in many types of tumor cells. DR5 binds to TRAIL and mediates TRAIL induced cell death. Overexpression of DR5 induces apoptosis and activates NF-kB.

    Tumor necrosis factor receptor superfamily member 10B Death receptor 5 TNF-related apoptosis-inducing ligand receptor 2, TRAIL receptor 2, TRAIL-R2 CD_antigen: CD262 KILLER/DR5,TRICK2A, TRICK2B, TRICKB Gene name: TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
    基因ID
    8795
    UniProt
    O14763
    途径
    p53 Pathway, Apoptosis, Positive Regulation of Endopeptidase Activity
You are here:
客服