SARS-CoV-2 Spike Protein (B.1.621 - mu, RBD) (His tag)
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- 抗原 See all SARS-CoV-2 Spike 蛋白
- SARS-CoV-2 Spike
- 蛋白类型
- Recombinant
- 产品特性
- B.1.621 - mu, RBD
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宿主
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Mu
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资源
- HEK-293 Cells
- 标记
- This SARS-CoV-2 Spike protein is labelled with His tag.
- 原理
- SARS-CoV-2 Spike RBD (R346K, E484K, N501Y), His Tag (MALS verified)
- 序列
- Arg 319 - Lys 537
- 特异性
- SARS-CoV-2 Spike RBD (R346K, E484K, N501Y)
- 产品特性
- SARS-CoV-2 Spike RBD, His Tag (SPD-C5221) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (R346K, E484K, N501Y). The mutations R346K, E484K, N501Y were identified in the SARS-CoV-2 Mu variant (Pango lineage: B.1.621).
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- 质量等级
- MALS verified
- Top Product
- Discover our top product SARS-CoV-2 Spike 蛋白
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- 应用备注
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.5 kDa. The protein migrates as 32-35 kDa under reducing (R) condition due to glycosylation.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
- 储存方法
- -20°C
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- 抗原
- SARS-CoV-2 Spike
- Abstract
- SARS-CoV-2 Spike 产品
- 别名
- E2 Protein, E2 glycoprotein precursor Protein, Surface Glycoprotein Protein, S Protein
- 背景
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Synonyms: Spike,S protein RBD,Spike glycoprotein Receptor-binding domain,S glycoprotein RBD,Spike protein RBD,
Description: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. - 分子量
- 26.5 kDa
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