SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (His tag,mFc Tag)
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Quick Overview for SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (His tag,mFc Tag) (ABIN6961147)
抗原
See all SARS-CoV-2 Spike (SARS-CoV-2 S) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 319-541, RBD
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标记
- This SARS-CoV-2 Spike protein is labelled with His tag,mFc Tag.
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原理
- Recombinant SARS-CoV-2 (2019-nCoV) S protein RBD with C-terminal mouse Fc and 6xHis tag
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特异性
- S protein RBD(Arg319-Phe541) mFc(Pro99-Lys330) 6xHis tag
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产品特性
- Extracellular Domain Protein
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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SARS-CoV-2 Spike (SARS-CoV-2 S) (Super Stable Trimer) protein (His tag)
SARS-CoV-2 S 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE. > 90 % as determined by SEC-MALS. ELISA
SARS-CoV-2 Spike (SARS-CoV-2 S) (AA 16-1188), (Trimer) (Active) protein (His-Avi Tag)SARS-CoV-2 S 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
SARS-CoV-2 Spike (SARS-CoV-2 S) (AA 319-532), (RBD) (Active) protein (His-Avi Tag)SARS-CoV-2 S 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
SARS-CoV-2 Spike (SARS-CoV-2 S) (AA 319-541), (B.1.1.529 - Omicron), (RBD) (Active) protein (His tag)SARS-CoV-2 S 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
SARS-CoV-2 Spike (SARS-CoV-2 S) (AA 319-541), (E484K), (K417N), (N501Y), (RBD) (Active) protein (His tag)SARS-CoV-2 S 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
SARS-CoV-2 Spike (SARS-CoV-2 S) (AA 319-541), (B.1.1.7 - alpha), (RBD) protein (Fc Tag)SARS-CoV-2 S 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining. IA, AM, ADA, ScA
SARS-CoV-2 Spike (SARS-CoV-2 S) (AA 319-541), (B.1.617.2 - delta), (RBD) protein (Fc Tag)SARS-CoV-2 S 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. IA, AM, ADA, ScA
SARS-CoV-2 Spike (SARS-CoV-2 S) (Super Stable Trimer) protein (His tag)SARS-CoV-2 S 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE. > 90 % as determined by SEC-MALS. ELISA
SARS-CoV-2 Spike (SARS-CoV-2 S) (AA 319-541), (B.1.640.2), (RBD) (Active) protein (His tag)SARS-CoV-2 S 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
SARS-CoV-2 Spike (SARS-CoV-2 S) (AA 16-1188), (D614G), (Trimer) (Active) protein (His-Avi Tag)SARS-CoV-2 S 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
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应用备注
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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说明
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The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please see Certificate of Analysis for specific instructions of reconstitution.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- SARS-CoV-2 Spike (SARS-CoV-2 S)
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别名
- SARS-CoV-2 S protein
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物质类
- Viral Protein
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背景
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S protein RBD,Spike glycoprotein Receptor-binding domain,S glycoprotein RBD,Spike protein RBD,COVID-19
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as Covid19 (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. The spike protein is a type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which accounts for recognizing the cell surface receptor, ACE2. S2 contains basic elements needed for the membrane fusion. Recent publications indicate that S1-RBD domain can induce virus neutralizing-antibody and T cell response. -
分子量
- predicted molecular mass of 52.2 kDa after removal of the signal peptide.
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基因ID
- 43740568
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UniProt
- P0DTC2
抗原
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