SARS-CoV-2 Spike Protein (B.1.617.1 - kappa) (rho-1D4 tag)
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- Key Features
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- Recombinant trimeric S protein of the SARS-CoV-2 variant of concern B.1.617.
- Contains E154K, L452R, E484Q, D614G, and P681R mutations characteristic for the SARS-CoV-2 kappa variant (B.1.617.1).
- 抗原 See all SARS-CoV-2 Spike 蛋白
- SARS-CoV-2 Spike
- 蛋白类型
- Recombinant
- 产品特性
- B.1.617.1 - kappa
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宿主
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Kappa
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资源
- HEK-293 Cells
- 标记
- This SARS-CoV-2 Spike protein is labelled with rho-1D4 tag.
- 应用范围
- ELISA, Ligand Binding Assay (LBA)
- 原理
- This is the spike protein of the mutant strain B.1.617, also commonly known as the "India" or "Kappa mutant".
- 序列
- 1286 amino acids (including Rho1D4 tag and linker)
- 特异性
- Mutation that differ from "original" SPIKE protein: G142D, E154K, L452R, E484Q, D614G, P681R, Q1071H
- 产品特性
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"SARS CoV-2 full-length Spike B.1.617 Mutation"
All viruses undergo fast mutations and adept quickly to the countermeasures that the immune systems creates against them. SARS-CoV-2 of the COVID-19 pandemic is no exception here. During the pandemic multiple mutant strains arose. To help the science combat these mutants we offer these mutant SPIKE proteins.
We offer the SPIKE protein of the mutants in full-length and active in their native trimeric form, stabilized with the LMNG detergent. - 纯度
- > 98% as determined by SDS-PAGE
- Top Product
- Discover our top product SARS-CoV-2 Spike 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Further modifications:
- furin cleavage site "682-RRAR|SV-687" mutated to "682-GSAG|PP-687"
- C-terminal Rho1D4 tag fused with spacer "GSSG" to protein sequence
Size: 1286 amino acids (including Rho1D4 tag and linker) - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 20 mM Hepes pH 7.5, 150 mM NaCl, 0.001 % LMNG
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Avoid freeze-thaw cycles
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- 抗原
- SARS-CoV-2 Spike
- 别名
- SARS2 Spike glycoprotein (SARS-CoV-2 Spike 产品)
- 别名
- E2 Protein, E2 glycoprotein precursor Protein, Surface Glycoprotein Protein, S Protein
- 物质类
- Viral Protein
- 背景
- All viruses undergo fast mutations and adapt quickly to the countermeasures that the immune systems creates. SARS-CoV-2 of the COVID-19 pandemic is no exception to this. During the pandemic multiple mutant strains arose.
- 分子量
- 142190.43 Da
- UniProt
- P0DTC2
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