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SARS-CoV-2 Spike Protein (B.1.617.1 - kappa) (rho-1D4 tag)

宿主: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Kappa 宿主: HEK-293 Cells Recombinant > 98% as determined by SDS-PAGE ELISA, LBA
产品编号 ABIN6976302
发货至: 中国
  • Key Features
    • Recombinant trimeric S protein of the SARS-CoV-2 variant of concern B.1.617.
    • Contains E154K, L452R, E484Q, D614G, and P681R mutations characteristic for the SARS-CoV-2 kappa variant (B.1.617.1).
    抗原 See all SARS-CoV-2 Spike 蛋白
    SARS-CoV-2 Spike
    蛋白类型
    Recombinant
    产品特性
    B.1.617.1 - kappa
    宿主
    • 190
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    SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Kappa
    资源
    • 174
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    HEK-293 Cells
    标记
    This SARS-CoV-2 Spike protein is labelled with rho-1D4 tag.
    应用范围
    ELISA, Ligand Binding Assay (LBA)
    原理
    This is the spike protein of the mutant strain B.1.617, also commonly known as the "India" or "Kappa mutant".
    序列
    1286 amino acids (including Rho1D4 tag and linker)
    特异性
    Mutation that differ from "original" SPIKE protein: G142D, E154K, L452R, E484Q, D614G, P681R, Q1071H
    产品特性
    "SARS CoV-2 full-length Spike B.1.617 Mutation"
    All viruses undergo fast mutations and adept quickly to the countermeasures that the immune systems creates against them. SARS-CoV-2 of the COVID-19 pandemic is no exception here. During the pandemic multiple mutant strains arose. To help the science combat these mutants we offer these mutant SPIKE proteins.
    We offer the SPIKE protein of the mutants in full-length and active in their native trimeric form, stabilized with the LMNG detergent.
    纯度
    > 98% as determined by SDS-PAGE
    Top Product
    Discover our top product SARS-CoV-2 Spike 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Further modifications:
    - furin cleavage site "682-RRAR|SV-687" mutated to "682-GSAG|PP-687"
    - C-terminal Rho1D4 tag fused with spacer "GSSG" to protein sequence
    Size: 1286 amino acids (including Rho1D4 tag and linker)

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    20 mM Hepes pH 7.5, 150 mM NaCl, 0.001 % LMNG
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Avoid freeze-thaw cycles
  • 抗原
    SARS-CoV-2 Spike
    别名
    SARS2 Spike glycoprotein (SARS-CoV-2 Spike 产品)
    别名
    E2 Protein, E2 glycoprotein precursor Protein, Surface Glycoprotein Protein, S Protein
    物质类
    Viral Protein
    背景
    All viruses undergo fast mutations and adapt quickly to the countermeasures that the immune systems creates. SARS-CoV-2 of the COVID-19 pandemic is no exception to this. During the pandemic multiple mutant strains arose.
    分子量
    142190.43 Da
    UniProt
    P0DTC2
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