SARS-CoV-2 Spike Protein (B.1.621 - mu) (rho-1D4 tag)
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- Key Features
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- Recombinant trimeric S protein of the SARS-CoV-2 variant of interest B.1.621 mu.
- Contains T95I, Y144S, Y145N, R346K, E484K, N501Y, D614G, P681H and D950N mutations characteristic for the SARS-CoV-2 mu variant (B.1.621).
- 抗原 See all SARS-CoV-2 Spike 蛋白
- SARS-CoV-2 Spike
- 蛋白类型
- Recombinant
- 产品特性
- B.1.621 - mu
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宿主
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Mu
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资源
- HEK-293 Cells
- 标记
- This SARS-CoV-2 Spike protein is labelled with rho-1D4 tag.
- 应用范围
- ELISA, Ligand Binding Assay (LBA)
- 原理
- This is the spike protein of the mutant strain B.1.621 (WHO variant of concern Mu).
- 特异性
- Mutations that differ from "original" SPIKE protein: T95I, Y144S, Y145N, R346K, N501Y, D614G, P681H, D950N
- 产品特性
- All viruses undergo fast mutations to adept quickly to the host's immune response and boost infectivity. SARS-CoV-2, the causative agent of COVID-19, is no exception. Over the course of the COVID-19 pandemic several predominant novel strains have already been identified. The B.1.621 Mu variant was first detected in Colombia in January 2021 and was added to the WHO list of SARS-CoV-2 variants of interest in August 2021.
- 纯化方法
- affinity chromatography
- 纯度
- > 98% as determined by SDS-PAGE
- Top Product
- Discover our top product SARS-CoV-2 Spike 蛋白
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- 说明
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Further modifications:
- furin cleavage site "682-RRAR|SV-687" mutated to "682-GSAG|PP-687"
- C-terminal Rho1D4 tag fused with spacer "GSSG" to protein sequence
Size: 1284 amino acids (including Rho1D4 tag and linker) 141903 Da - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 20 mM Hepes pH 7.5; 150 mM NaCl, 0.001 % LMNG
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Avoid freeze-thaw cycles
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- 抗原
- SARS-CoV-2 Spike
- 别名
- SARS2 Spike glycoprotein (SARS-CoV-2 Spike 产品)
- 别名
- E2 Protein, E2 glycoprotein precursor Protein, Surface Glycoprotein Protein, S Protein
- 物质类
- Viral Protein
- UniProt
- P0DTC2
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