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FGFR3 抗体 (N-Term)

FGFR3 适用: 人, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043988
发货至: 中国
  • 抗原 See all FGFR3 抗体
    FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
    抗原表位
    • 17
    • 15
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 110-129, N-Term
    适用
    • 112
    • 50
    • 41
    • 4
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 105
    • 7
    • 1
    克隆类型
    • 92
    • 21
    多克隆
    标记
    • 41
    • 12
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This FGFR3 antibody is un-conjugated
    应用范围
    • 83
    • 43
    • 42
    • 13
    • 13
    • 10
    • 9
    • 9
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    原理
    Rabbit IgG polyclonal antibody for Fibroblast growth factor receptor 3(FGFR3) detection. Tested with WB, IHC-P, ICC in Human,Rat.
    序列
    RQRLTQRVLC HFSVRVTDAP
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Fibroblast growth factor receptor 3(FGFR3) detection. Tested with WB, IHC-P, ICC in Human,Rat.
    Gene Name: fibroblast growth factor receptor 3
    Protein Name: Fibroblast growth factor receptor 3
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human FGFR3(110-129aa RQRLTQRVLCHFSVRVTDAP), different from the related rat sequence by two amino acids, and from the related mouse sequence by three amino acids.
    亚型
    IgG
    Top Product
    Discover our top product FGFR3 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Rat
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
    别名
    FGFR3 (FGFR3 产品)
    别名
    FGFR3 antibody, LOC100034114 antibody, ACH antibody, CD333 antibody, CEK2 antibody, HSFGFR3EX antibody, JTK4 antibody, FR3 antibody, Fgfr-3 antibody, Flg-2 antibody, HBGFR antibody, Mfr3 antibody, sam3 antibody, fc27h01 antibody, wu:fc27h01 antibody, fibroblast growth factor receptor 3 antibody, fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog antibody, FGFR3 antibody, fgfr3.S antibody, Fgfr3 antibody, fgfr3 antibody
    背景
    Fibroblast growth factor receptor 3, also known as CD333, is a protein that in humans is encoded by the FGFR3 gene. This gene encodes a member of the fibroblast growth factor receptor(FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. The FGFR3 gene is mapped to the HD region on chromosome 4p16.3. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia.

    Synonyms: ACH antibody|CD 333 antibody|CD333 antibody|CD333 antigen antibody|CEK 2 antibody|CEK2 antibody|FGFR 3 antibody|FGFR-3 antibody|FGFR3 antibody|FGFR3_HUMAN antibody|Fibroblast growth factor receptor 3(achondroplasia thanatophoric dwarfism) antibody|Fibroblast growth factor receptor 3 antibody|Heparin binding growth factor receptor antibody|HSFGFR3EX antibody|Hydroxyaryl protein kinase antibody|JTK 4 antibody|JTK4 antibody|MFR 3 antibody|SAM 3 antibody|Tyrosine kinase JTK 4 antibody|Tyrosine kinase JTK4 antibody|Z FGFR 3 antibody
    UniProt
    P22607
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding
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