FGFR3 抗体 (AA 131-180)
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北京 101111
Quick Overview for FGFR3 抗体 (AA 131-180) (ABIN1533273)
抗原
See all FGFR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 131-180
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原理
- FGFR-3 Antibody
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特异性
- FGFR-3 Polyclonal Antibody detects endogenous levels of FGFR-3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human FGFR3. AA range:131-180
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亚型
- IgG
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anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 529-694) antibody
FGFR3 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2H10B4 unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 166-375) antibodyFGFR3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 39-138) antibodyFGFR3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (N-Term) antibodyFGFR3 适用: 人, 大鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 529-694) antibodyFGFR3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1E3F9 unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (C-Term) antibodyFGFR3 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 23-375) antibodyFGFR3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) antibodyKD Validated FGFR3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2965 unconjugated Recombinant Antibody
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 776-806), (C-Term) antibodyFGFR3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01572 unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) antibodyFGFR3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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: "Fibroblast growth factor-2 (Fgf2) is an important factor that maintains cellular immaturity and contributes to aggressiveness of osteosarcoma." in: Molecular cancer research : MCR, (2012) (PubMed).
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- FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
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别名
- FGFR3
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背景
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Synonyms: FGFR3, JTK4, Fibroblast growth factor receptor 3, FGFR-3, CD antigen CD333
Background: This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dys
Gene Name: FGFR3
Protein Name: Fibroblast growth factor receptor 3
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分子量
- 87 kDa
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基因ID
- 2261
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OMIM
- 134934
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UniProt
- P22607
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding
抗原
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