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FGFR3 抗体 (AA 39-138)

FGFR3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1679839
发货至: 中国
  • 抗原 See all FGFR3 抗体
    FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
    抗原表位
    • 17
    • 15
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 39-138
    适用
    • 112
    • 50
    • 42
    • 4
    • 1
    • 1
    • 1
    宿主
    • 105
    • 7
    • 1
    克隆类型
    • 92
    • 21
    多克隆
    标记
    • 41
    • 12
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This FGFR3 antibody is un-conjugated
    应用范围
    • 83
    • 43
    • 41
    • 13
    • 13
    • 10
    • 10
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    序列
    PGPEPGQQEQ LVFGSGDAVE LSCPPPGGGP MGPTVWVKDG TGLVPSERVL VGPQRLQVLN ASHEDSGAYS CRQRLTQRVL CHFSVRVTDA PSSGDDEDGE
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 39-138 of human FGFR3 (NP_000133.1).
    亚型
    IgG
    Top Product
    Discover our top product FGFR3 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
    别名
    FGFR3 (FGFR3 产品)
    别名
    FGFR3 antibody, LOC100034114 antibody, ACH antibody, CD333 antibody, CEK2 antibody, HSFGFR3EX antibody, JTK4 antibody, FR3 antibody, Fgfr-3 antibody, Flg-2 antibody, HBGFR antibody, Mfr3 antibody, sam3 antibody, fc27h01 antibody, wu:fc27h01 antibody, fibroblast growth factor receptor 3 antibody, fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog antibody, FGFR3 antibody, fgfr3.S antibody, Fgfr3 antibody, fgfr3 antibody
    背景
    This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described.,ACH,CD333,CEK2,HSFGFR3EX,JTK4,FGFR3,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,ESC Pluripotency and Differentiation,Immunology & Inflammation,CD markers,Stem Cells,Neural Stem Cells,Cardiovascular,Angiogenesis,FGFR3
    分子量
    75 kDa/85 kDa/87 kDa/88 kDa
    基因ID
    2261
    UniProt
    P22607
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding
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