SIGMAR1 抗体
(sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor\; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| SIGMAR1 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| SIGMAR1 抗体 (AA 1-154) | 人, 小鼠, 大鼠, 猴 | 兔 Polyclonal |
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| SIGMAR1 抗体 (AA 21-120) | 人 | 兔 Polyclonal |
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| SIGMAR1 抗体 (AA 118-147) | 人, 小鼠 | 兔 Polyclonal |
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| SIGMAR1 抗体 (AA 112-169) | 人 | 兔 Polyclonal |
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| SIGMAR1 抗体 (AA 31-80) | 人 | 兔 Polyclonal |
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| SIGMAR1 抗体 (C-Term, Intracellular) | 人 | 兔 Polyclonal |
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| SIGMAR1 抗体 (AA 47-81) | 人 | 兔 Polyclonal |
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| SIGMAR1 抗体 (AA 112-169) (FITC) | 人 | 兔 Polyclonal |
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| SIGMAR1 抗体 (AA 112-169) (Biotin) | 人 | 兔 Polyclonal |
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| SIGMAR1 抗体 (AA 112-169) (HRP) | 人 | 兔 Polyclonal |
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| SIGMAR1 抗体 (C-Term, Intracellular) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| SIGMAR1 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| SIGMAR1 抗体 (AA 1-154) (APC) | 人, 小鼠, 大鼠, 猴 | 兔 Polyclonal |
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| SIGMAR1 抗体 (AA 1-154) | 人, 小鼠, 大鼠, 猴 | 兔 Polyclonal |
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| SIGMAR1 抗体 (AA 1-154) (HRP) | 人, 小鼠, 大鼠, 猴 | 兔 Polyclonal |
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| SIGMAR1 抗体 (AA 1-154) (Biotin) | 人, 小鼠, 大鼠, 猴 | 兔 Polyclonal |
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| SIGMAR1 抗体 (AA 1-154) (FITC) | 人, 小鼠, 大鼠, 猴 | 兔 Polyclonal |
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| SIGMAR1 抗体 (AA 1-154) (Fluoro550) | 人, 小鼠, 大鼠, 猴 | 兔 Polyclonal |
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| SIGMAR1 抗体 (AA 1-154) (Cy3) | 人, 小鼠, 大鼠, 猴 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
1 reference - 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB14256
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 47-81, N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-154
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 21-120
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB14335
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 118-147
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 112-169
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 31-80
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- M (Molecule: 有验证图片)
KO 验证
- 质量等级
- KO Validated
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 113-126, C-Term, Intracellular
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 47-81
Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 112-169
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 112-169
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 112-169
Primary Antibody
- M (Molecule: 有验证图片)
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
KO 验证
- 质量等级
- Carrier-free, KO Validated
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 113-126, C-Term, Intracellular
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- APC
- 抗体亚型
- IgG
- 抗原表位
- AA 1-154
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- Carrier-free
- 适用
- 人, 小鼠, 大鼠, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-154
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 1-154
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 1-154
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 1-154
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Fluoro550
- 抗体亚型
- IgG
- 抗原表位
- AA 1-154
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy3
- 抗体亚型
- IgG
- 抗原表位
- AA 1-154
Latest Publications for our SIGMAR1 抗体
: "Sigma-1 Receptor Antagonist (BD1047) Decreases Cathepsin B Secretion in HIV-Infected Macrophages Exposed to Cocaine." in: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, (2018) (PubMed).
: "TRPV1 channels and the progesterone receptor Sig-1R interact to regulate pain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 7, pp. E1657-E1666, (2018) (PubMed).
: "The SigmaR1 chaperone drives breast and colorectal cancer cell migration by tuning SK3-dependent Ca2+ homeostasis. ..." in: Oncogene, Vol. 36, Issue 25, pp. 3640-3647, (2017) (PubMed).
: "Modeling tandem AAG8-MEK inhibition in melanoma cells." in: Cancer medicine, Vol. 3, Issue 3, pp. 710-8, (2014) (PubMed).
: "The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation." in: The Journal of clinical investigation, Vol. 122, Issue 12, pp. 4569-79, (2012) (PubMed).
: "An unambiguous assay for the cloned human sigma1 receptor reveals high affinity interactions with dopamine D4 receptor selective compounds and a distinct structure-affinity relationship for ..." in: European journal of pharmacology, Vol. 578, Issue 2-3, pp. 123-36, (2008) (PubMed).
: "Irreversible blockade of sigma-1 receptors by haloperidol and its metabolites in guinea pig brain and SH-SY5Y human neuroblastoma cells." in: Journal of neurochemistry, Vol. 102, Issue 3, pp. 812-25, (2007) (PubMed).
: "Neuro(active)steroids actions at the neuromodulatory sigma1 (sigma1) receptor: biochemical and physiological evidences, consequences in neuroprotection." in: Pharmacology, biochemistry, and behavior, Vol. 84, Issue 4, pp. 581-97, (2006) (PubMed).
: "TRPV1 channels and the progesterone receptor Sig-1R interact to regulate pain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 7, pp. E1657-E1666, (2018) (PubMed).
: "The SigmaR1 chaperone drives breast and colorectal cancer cell migration by tuning SK3-dependent Ca2+ homeostasis. ..." in: Oncogene, Vol. 36, Issue 25, pp. 3640-3647, (2017) (PubMed).
: "Modeling tandem AAG8-MEK inhibition in melanoma cells." in: Cancer medicine, Vol. 3, Issue 3, pp. 710-8, (2014) (PubMed).
: "The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation." in: The Journal of clinical investigation, Vol. 122, Issue 12, pp. 4569-79, (2012) (PubMed).
: "An unambiguous assay for the cloned human sigma1 receptor reveals high affinity interactions with dopamine D4 receptor selective compounds and a distinct structure-affinity relationship for ..." in: European journal of pharmacology, Vol. 578, Issue 2-3, pp. 123-36, (2008) (PubMed).
: "Irreversible blockade of sigma-1 receptors by haloperidol and its metabolites in guinea pig brain and SH-SY5Y human neuroblastoma cells." in: Journal of neurochemistry, Vol. 102, Issue 3, pp. 812-25, (2007) (PubMed).
: "Neuro(active)steroids actions at the neuromodulatory sigma1 (sigma1) receptor: biochemical and physiological evidences, consequences in neuroprotection." in: Pharmacology, biochemistry, and behavior, Vol. 84, Issue 4, pp. 581-97, (2006) (PubMed).
Aliases for SIGMAR1 抗体
sigma non-opioid intracellular receptor 1 (SIGMAR1) 抗体sigma non-opioid intracellular receptor 1 (Sigmar1) 抗体
sigma non-opioid intracellular receptor 1 L homeolog (sigmar1.L) 抗体
sigma non-opioid intracellular receptor 1 (sigmar1) 抗体
AL024364 抗体
ALS16 抗体
mSigmaR1 抗体
OPRS1 抗体
Oprs1 抗体
oprs1 抗体
SIG-1R 抗体
sigma1R 抗体
Sigma1R 抗体
SR-BP 抗体
SR-BP1 抗体
SRBP 抗体
zgc:56378 抗体
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