SIGMAR1 抗体 (AA 1-154)
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北京 101111
Quick Overview for SIGMAR1 抗体 (AA 1-154) (ABIN7599011)
抗原
See all SIGMAR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-154
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原理
- Anti-Sigma1-receptor/SIGMAR1 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-Sigma1-receptor/SIGMAR1 Antibody. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Sigma1-receptor/SIGMAR1 recombinant protein (Position: G1-H154).
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亚型
- IgG
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应用备注
- Western blot, 0.1-0.25 μg/mL, Human, Monkey, Mouse Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
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别名
- SIGMAR1
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背景
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Background: The sigma-1 receptor (σ1R), one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor. In humans, the σ1 receptor is encoded by the SIGMAR1 gene. This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor, it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
Gene Full Name: sigma non-opioid intracellular receptor 1
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分子量
- 25 kDa
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基因ID
- 10280
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UniProt
- Q99720
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途径
- SARS-CoV-2 Protein Interactome
抗原
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