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SIGMAR1 抗体 (AA 1-154) (Biotin)

This 兔 多克隆 antibody specifically detects SIGMAR1 in WB, ELISA 和 IHC. It exhibits reactivity toward 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN8037287
发货至: 中国
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Quick Overview for SIGMAR1 抗体 (AA 1-154) (Biotin) (ABIN8037287)

抗原

See all SIGMAR1 抗体
SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

适用

人, 小鼠, 大鼠, 猴

宿主

  • 33

克隆类型

  • 33
多克隆

标记

  • 13
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIGMAR1 antibody is conjugated to Biotin

应用范围

  • 13
  • 10
  • 10
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 12
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-154

    原理

    Anti-Sigma1-receptor/SIGMAR1 Antibody Biotin Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Sigma1-receptor/SIGMAR1 recombinant protein (Position: G1-H154).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

    别名

    SIGMAR1

    背景

    Background: The sigma-1 receptor (σ1R), one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor. In humans, the σ1 receptor is encoded by the SIGMAR1 gene. This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor, it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.

    Gene Full Name: sigma non-opioid intracellular receptor 1

    基因ID

    10280

    UniProt

    Q99720

    途径

    SARS-CoV-2 Protein Interactome
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