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Siglece 抗体

(Sialic Acid Binding Ig-Like Lectin E (Siglece))
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.

Active filters:

  • 抗原: Siglec E (Siglece)
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN1818480
Siglec E 抗体 Siglece · Primary Antibody 小鼠 大鼠 Monoclonal 克隆位点 8D2
  • FACS (Flow Cytometry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
  • 100 μg
发货至: 中国
ABIN1818481
Siglec E 抗体 (FITC) Siglece · Primary Antibody 小鼠 大鼠 Monoclonal 克隆位点 8D2
  • FACS (Flow Cytometry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
  • 1 mL
发货至: 中国
Primary Antibody
  • FACS (Flow Cytometry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
适用
小鼠
宿主
大鼠
克隆形成能力
Monoclonal
克隆
8D2
标记
unconjugated
抗体亚型
IgG2b
产品编号 ABIN1818480
Primary Antibody
  • FACS (Flow Cytometry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
适用
小鼠
宿主
大鼠
克隆形成能力
Monoclonal
克隆
8D2
标记
FITC
抗体亚型
IgG2b
产品编号 ABIN1818481

Latest Publications for our Siglece 抗体

Smith, Deutzmann, Correa, Delaveris, Dhanasekaran, Dove, Sullivan, Wisnovsky, Stark, Pluvinage, Swaminathan, Riley, Rajan, Majeti, Felsher, Bertozzi: "MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 120, Issue 11, pp. e2215376120, (2023) (PubMed).

Dharmadhikari, Stolz, Hauke, Morgan, Varki, de Koning, Kelm, Maedler: "Siglec-7 restores β-cell function and survival and reduces inflammation in pancreatic islets from patients with diabetes." in: Scientific reports, Vol. 7, pp. 45319, (2017) (PubMed).

Wu, Ren, Chen: "Siglec-E Negatively Regulates the Activation of TLR4 by Controlling Its Endocytosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 8, pp. 3336-3347, (2016) (PubMed).

Aliases for Siglece 抗体

sialic acid binding Ig-like lectin E (Siglece) 抗体
Cd170 抗体
mSiglec-E 抗体
Siglec5 抗体
Siglec9 抗体
Siglec12 抗体
Siglecl1 抗体
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