SIGMAR1 抗体 (AA 1-154) (Fluoro550)
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北京 101111
Quick Overview for SIGMAR1 抗体 (AA 1-154) (Fluoro550) (ABIN8037290)
抗原
See all SIGMAR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-154
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原理
- Anti-Sigma1-receptor/SIGMAR1 Antibody Fluoro550 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Sigma1-receptor/SIGMAR1 recombinant protein (Position: G1-H154).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
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别名
- SIGMAR1
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背景
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Background: The sigma-1 receptor (σ1R), one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor. In humans, the σ1 receptor is encoded by the SIGMAR1 gene. This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor, it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
Gene Full Name: sigma non-opioid intracellular receptor 1
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基因ID
- 10280
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UniProt
- Q99720
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途径
- SARS-CoV-2 Protein Interactome
抗原
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