Poliovirus Receptor Protein (PVR) (AA 21-343) (Fc Tag)
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- 抗原 See all Poliovirus Receptor (PVR) 蛋白
- Poliovirus Receptor (PVR)
- 蛋白类型
- Recombinant
- 产品特性
- AA 21-343
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Poliovirus Receptor protein is labelled with Fc Tag.
- 原理
- Human CD155/PVR Protein
- 序列
- Trp21-Asn343
- 产品特性
- Recombinant Human CD155/PVR Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Trp21-Asn343.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human TIGIT, His Tag at 0.5μg/ml (100μl/Well). Dose response curve for Human CD155, hFc Tag with the EC50 of 0.18μg/ml determined by ELISA. The affinity constant of 0.958 μM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product PVR 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Poliovirus Receptor (PVR)
- 别名
- CD155 (PVR 产品)
- 别名
- PVR Protein, CD155 Protein, HVED Protein, NECL5 Protein, Necl-5 Protein, PVS Protein, TAGE4 Protein, 3830421F03Rik Protein, D7Ertd458e Protein, Taa1 Protein, Tage4 Protein, mE4 Protein, necl-5 Protein, poliovirus receptor Protein, PVR Protein, Pvr Protein
- 背景
- CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the "poliovirus receptor," or PVR.
- 分子量
- 61.8 kDa. Due to glycosylation, the protein migrates to 75-100 kDa based on Tris-Bis PAGE result.
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
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