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Cancer Immune Checkpoints

Cancer Immune Checkpoints

Inhibitory T-Cell Receptors

LAG3 (Lymphocyte-Activation Gene 3):

VISTA (V-type immunoglobulin domain-containing suppressor of T-cell activation):

TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains):

BTLA (B and T Lymphocyte Associated):

KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3):

TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4):

TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14):

Major Histocompatibility Complex

HLA-A (Major Histocompatibility Complex, Class I, A):

MR1 (Major Histocompatibility Complex, Class I-Related):

CIITA (Class II, Major Histocompatibility Complex, Transactivator):

HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G):

HLA-B (Major Histocompatibility Complex, Class I, B):

HLA-ABC (HLA-ABC):

HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha):

HLA-DMB (Major Histocompatibility Complex, Class II, DM beta):

HLA-DOB (Major Histocompatibility Complex, Class II, DO beta):

HLA-DPA1 (Major Histocompatibility Complex, Class II, DP alpha 1):

HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1):

HLA-DQA1 (Major Histocompatibility Complex, Class II, DQ alpha 1):

HLA-DQB1 (Major Histocompatibility Complex, Class II, DQ beta 1):

HLA-DRB1 (Major Histocompatibility Complex, Class II, DR beta 1):

HLA-DRB3 (Major Histocompatibility Complex, Class II, DR beta 3):

HLA-DRB5 (Major Histocompatibility Complex, Class II, DR beta 5):

PTCRA (Pre T-Cell Antigen Receptor alpha):

Stimulatory T-Cell Receptors

CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4):

TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4):

ACVR2B (Activin A Receptor, Type IIB):

ICOS (Inducible T-Cell Co-Stimulator):

TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9):

TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18):

TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4):

Cytokine

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