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IL12 蛋白

(Interleukin 12 (IL12))
This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008].
Interleukin 12 (IL12) (AA 23-219), (AA 23-328) (Active) protein Interleukin 12 (IL12) (AA 23-219), (AA 23-328) (Active) protein Interleukin 12 (IL12) (AA 23-219), (AA 23-328) (Active) protein (ABIN2018013)

IL12 宿主: 人 宿主: HEK-293T Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active

Interleukin 12 (IL12) (AA 23-328) (Active) protein (His tag,DYKDDDDK Tag) Interleukin 12 (IL12) (AA 23-328) (Active) protein (His tag,DYKDDDDK Tag) Interleukin 12 (IL12) (AA 23-328) (Active) protein (His tag,DYKDDDDK Tag) (ABIN2181328)

IL12 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active

Interleukin 12 (IL12) (AA 23-328) (Active) protein (His tag,AVI tag,DYKDDDDK Tag,Biotin) Interleukin 12 (IL12) (AA 23-328) (Active) protein (His tag,AVI tag,DYKDDDDK Tag,Biotin) Interleukin 12 (IL12) (AA 23-328) (Active) protein (His tag,AVI tag,DYKDDDDK Tag,Biotin) (ABIN6973104)

IL12 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active

IL12 蛋白 by Origin

Find IL12 蛋白 for a variety of species such as anti-Human IL12, anti-Mouse IL12, anti-Rat IL12. The species listed below are among those available. Click on a link to go to the corresponding products.

IL12 蛋白 by Source

Find IL12 蛋白 with a specific Source. The Source listed below are among those available. Click on a link to go to the corresponding products.

IL12 蛋白 by 蛋白类型

Find IL12 蛋白 with a specific 蛋白类型. The 蛋白类型 listed below are among those available. Click on a link to go to the corresponding products.

IL12 蛋白 by 应用范围

Find IL12 蛋白 validated for a specific application such as ELISA, SDS, WB, BCA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

IL12 蛋白 by 生物活性

Find IL12 蛋白 with a specific 生物活性. The 生物活性 listed below are among those available. Click on a link to go to the corresponding products.

Popular IL12 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (2)
Cat. No. ABIN6700019
Quantity 2 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN5853918
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source Human Cells
Validations
Cat. No. ABIN7196374
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN6253328
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source CHO Cells
Validations
Cat. No. ABIN2018061
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7123545
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source CHO Cells
Validations
Cat. No. ABIN2018058
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN2129940
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source CHO Cells
Validations
Cat. No. ABIN6253330
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source CHO Cells
Validations
Cat. No. ABIN6253329
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1112288
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
Cat. No. ABIN2129944
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN804271
Quantity 1 mg
Datasheet Datasheet
Reactivity Human, Mouse
Source Insect Cells
Validations
Cat. No. ABIN2129946
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source
Validations
Cat. No. ABIN1111712
Quantity 2 μg
Datasheet Datasheet

Latest Publications for our IL12 蛋白

Ling, Gately, Gubler, Stern, Lin, Hollfelder, Su, Pan, Hakimi: "Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 1, pp. 116-27, (1995) (PubMed).

DAndrea, Aste-Amezaga, Valiante, Ma, Kubin, Trinchieri: "Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells." in: The Journal of experimental medicine, Vol. 178, Issue 3, pp. 1041-8, (1993) (PubMed).

Schoenhaut, Chua, Wolitzky, Quinn, Dwyer, McComas, Familletti, Gately, Gubler: "Cloning and expression of murine IL-12." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 11, pp. 3433-40, (1992) (PubMed).

DAndrea, Rengaraju, Valiante, Chehimi, Kubin, Aste, Chan, Kobayashi, Young, Nickbarg: "Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells." in: The Journal of experimental medicine, Vol. 176, Issue 5, pp. 1387-98, (1992) (PubMed).

Aliases for IL12 蛋白

interleukin 12B (IL12B) 蛋白
interleukin 12A (IL12A) 蛋白
interleukin 12b (Il12b) 蛋白
interleukin 12B (Il12b) 蛋白
interleukin 12a (Il12a) 蛋白
interleukin 12A (Il12a) 蛋白
Interleukin 12 level (IL12) 蛋白
interleukin 12a (il12a) 蛋白
CLMF 蛋白
CLMF2 蛋白
IL-12 蛋白
IL-12 p35 蛋白
Il-12a 蛋白
IL-12B 蛋白
Il-12b 蛋白
IL-12p35 蛋白
Il-12p40 蛋白
IL-12p40 蛋白
Il12 蛋白
IL12B 蛋白
Il12p40 蛋白
IL12p40 蛋白
Ll12a 蛋白
LOC100217488 蛋白
NKSF 蛋白
NKSF2 蛋白
p35 蛋白
p40 蛋白
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