CD130/gp130 抗体
(Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2010].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| CD130/gp130 抗体 (C-Term) | 人 | 兔 Polyclonal |
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| CD130/gp130 抗体 (AA 73-231) | 人, 猴 | 小鼠 Monoclonal |
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|
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| CD130/gp130 抗体 (AA 392-566) | 人 | 兔 Polyclonal |
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| CD130/gp130 抗体 (AA 238-500) | 小鼠 | 兔 Polyclonal |
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| CD130/gp130 抗体 (AA 26-323) | 大鼠 | 兔 Polyclonal |
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| CD130/gp130 抗体 (pSer782) | 人 | 兔 Polyclonal |
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| CD130/gp130 抗体 (AA 651-750) | 小鼠 | 兔 Polyclonal |
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| Recombinant CD130/gp130 抗体 (AA 23-323) | 人 | 兔 Monoclonal |
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| CD130/gp130 抗体 (AA 678-857) | 人 | 兔 Polyclonal |
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|
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| CD130/gp130 抗体 (AA 678-857) | 人 | 兔 Polyclonal |
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| CD130/gp130 抗体 | 人 | 小鼠 Monoclonal |
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| CD130/gp130 抗体 | 人 | 小鼠 Monoclonal |
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| CD130/gp130 抗体 (AA 23-122) | 人 | 小鼠 Monoclonal |
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| CD130/gp130 抗体 | 人 | 小鼠 Monoclonal |
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| CD130/gp130 抗体 | 人 | 小鼠 Monoclonal |
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| CD130/gp130 抗体 (AA 23-122) | 人 | 小鼠 Monoclonal |
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|
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| CD130/gp130 抗体 (pTyr905) | 人 | 兔 Polyclonal |
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| CD130/gp130 抗体 (C-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| CD130/gp130 抗体 (AA 868-918) | 人, 小鼠 | 兔 Polyclonal |
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| CD130/gp130 抗体 (Ser552) | 人, 小鼠 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB17993
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 871-899, C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- ELISA (ELISA: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 猴
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 8D4D2
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 73-231
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 392-566
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- WB (Western Blotting: 有验证图片)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 238-500
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 26-323
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pSer782
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
2 references - 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 651-750
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ICC (Immunocytochemistry: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- BLR114H
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
- 抗原表位
- AA 23-323
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 678-857
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
KO 验证
- 质量等级
- KO Validated
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 678-857
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- Func (Functional Studies: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- B-P4
- 标记
- unconjugated
- 抗体亚型
- IgG1 kappa
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- Func (Functional Studies: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- B-R3
- 标记
- unconjugated
- 抗体亚型
- IgG2a, kappa
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 4A4
- 标记
- unconjugated
- 抗体亚型
- IgG2a
- 抗原表位
- AA 23-122
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- B-R3
- 标记
- unconjugated
- 抗体亚型
- IgG2a, kappa
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- ELISA (ELISA: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- B-K11
- 标记
- unconjugated
- 抗体亚型
- IgG2b, kappa
Primary Antibody
- ELISA (ELISA: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2A4
- 标记
- unconjugated
- 抗体亚型
- IgG2b
- 抗原表位
- AA 23-122
Primary Antibody
- DB (Dot Blot: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB21495
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- pTyr905
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 868-918
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Ser552
Latest Publications for our CD130/gp130 抗体
: "Granulocytes Are Unresponsive to IL-6 Due to an Absence of gp130." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 10, pp. 3547-3555, (2018) (PubMed).
: "Cachexia-associated adipose loss induced by tumor-secreted leukemia inhibitory factor is counterbalanced by decreased leptin." in: JCI insight, Vol. 3, Issue 14, (2018) (PubMed).
: "Interleukin‑6 induces an epithelial‑mesenchymal transition phenotype in human adamantinomatous craniopharyngioma cells and promotes tumor cell migration." in: Molecular medicine reports, Vol. 15, Issue 6, pp. 4123-4131, (2018) (PubMed).
: "Distinct Effects of IL-6 Classic and Trans-Signaling in Bone Fracture Healing." in: The American journal of pathology, Vol. 188, Issue 2, pp. 474-490, (2017) (PubMed).
: "Dendritic cell MST1 inhibits Th17 differentiation." in: Nature communications, Vol. 8, pp. 14275, (2017) (PubMed).
: "Epstein-Barr virus-induced gene 3 (EBI3) can mediate IL-6trans-signaling." in: The Journal of biological chemistry, Vol. 292, Issue 16, pp. 6644-6656, (2017) (PubMed).
: "TNFR-Associated Factors 2 and 5 Differentially Regulate the Instructive IL-6 Receptor Signaling Required for Th17 Development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 196, Issue 10, pp. 4082-9, (2016) (PubMed).
: "MicroRNA-146a regulates ICOS-ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres." in: Nature communications, Vol. 6, pp. 6436, (2015) (PubMed).
: "Oncostatin M acting via OSMR, augments the actions of IL-1 and TNF in synovial fibroblasts." in: Cytokine, Vol. 68, Issue 2, pp. 101-9, (2014) (PubMed).
: "Innate Stat3-mediated induction of the antimicrobial protein Reg3? is required for host defense against MRSA pneumonia." in: The Journal of experimental medicine, Vol. 210, Issue 3, pp. 551-61, (2013) (PubMed).
: "Cachexia-associated adipose loss induced by tumor-secreted leukemia inhibitory factor is counterbalanced by decreased leptin." in: JCI insight, Vol. 3, Issue 14, (2018) (PubMed).
: "Interleukin‑6 induces an epithelial‑mesenchymal transition phenotype in human adamantinomatous craniopharyngioma cells and promotes tumor cell migration." in: Molecular medicine reports, Vol. 15, Issue 6, pp. 4123-4131, (2018) (PubMed).
: "Distinct Effects of IL-6 Classic and Trans-Signaling in Bone Fracture Healing." in: The American journal of pathology, Vol. 188, Issue 2, pp. 474-490, (2017) (PubMed).
: "Dendritic cell MST1 inhibits Th17 differentiation." in: Nature communications, Vol. 8, pp. 14275, (2017) (PubMed).
: "Epstein-Barr virus-induced gene 3 (EBI3) can mediate IL-6trans-signaling." in: The Journal of biological chemistry, Vol. 292, Issue 16, pp. 6644-6656, (2017) (PubMed).
: "TNFR-Associated Factors 2 and 5 Differentially Regulate the Instructive IL-6 Receptor Signaling Required for Th17 Development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 196, Issue 10, pp. 4082-9, (2016) (PubMed).
: "MicroRNA-146a regulates ICOS-ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres." in: Nature communications, Vol. 6, pp. 6436, (2015) (PubMed).
: "Oncostatin M acting via OSMR, augments the actions of IL-1 and TNF in synovial fibroblasts." in: Cytokine, Vol. 68, Issue 2, pp. 101-9, (2014) (PubMed).
: "Innate Stat3-mediated induction of the antimicrobial protein Reg3? is required for host defense against MRSA pneumonia." in: The Journal of experimental medicine, Vol. 210, Issue 3, pp. 551-61, (2013) (PubMed).
Aliases for CD130/gp130 抗体
interleukin 6 signal transducer (IL6ST) 抗体interleukin 6 signal transducer (Il6st) 抗体
interleukin 6 signal transducer (il6st) 抗体
5133400A03Rik 抗体
AA389424 抗体
Ac1055 抗体
BB405851 抗体
CD130 抗体
CDW130 抗体
D13Ertd699e 抗体
GP130 抗体
gp130 抗体
Gp130 抗体
IL-6 抗体
IL-6RB 抗体
Il-6rb 抗体
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