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CD130/gp130 抗体 (AA 73-231)

IL6ST 适用: 人, 猴 WB, IHC, ELISA, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 8D4D2 unconjugated
产品编号 ABIN7193398
发货至: 中国
  • 抗原 See all CD130/gp130 (IL6ST) 抗体
    CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
    抗原表位
    • 35
    • 16
    • 14
    • 11
    • 8
    • 7
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 73-231
    适用
    • 136
    • 66
    • 55
    • 20
    • 18
    • 18
    • 17
    • 3
    • 1
    • 1
    人, 猴
    宿主
    • 114
    • 24
    • 3
    • 2
    • 1
    小鼠
    克隆类型
    • 116
    • 28
    单克隆
    标记
    • 50
    • 15
    • 9
    • 8
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD130/gp130 antibody is un-conjugated
    应用范围
    • 98
    • 37
    • 36
    • 28
    • 27
    • 26
    • 18
    • 13
    • 9
    • 8
    • 8
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human CD130 (AA: extra 73-231) expressed in E. coli.
    克隆位点
    8D4D2
    亚型
    IgG1
    Top Product
    Discover our top product IL6ST Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
    限制
    仅限研究用
  • 缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • 抗原
    CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
    别名
    CD130 (IL6ST 产品)
    别名
    CD130 antibody, CDW130 antibody, GP130 antibody, IL-6RB antibody, 5133400A03Rik antibody, AA389424 antibody, BB405851 antibody, D13Ertd699e antibody, gp130 antibody, Ac1055 antibody, Gp130 antibody, Il-6rb antibody, IL-6 antibody, interleukin 6 signal transducer antibody, IL6ST antibody, Il6st antibody, il6st antibody
    背景

    Description: The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014]

    Aliases: IL6ST, GP130, CDW130, IL-6RB

    分子量
    103.5 kDa
    基因ID
    3572
    途径
    JAK/STAT Signaling, Cellular Glucan Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Cancer Immune Checkpoints
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