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CD130/gp130 抗体 (pSer782)

IL6ST 适用: 人, 大鼠 WB, ELISA, IF (p), ICC, IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1714257
发货至: 中国
  • 抗原 See all CD130/gp130 (IL6ST) 抗体
    CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
    抗原表位
    • 34
    • 16
    • 14
    • 11
    • 8
    • 7
    • 6
    • 6
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    • 3
    • 3
    • 3
    • 2
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    pSer782
    适用
    • 137
    • 65
    • 55
    • 20
    • 18
    • 18
    • 17
    • 4
    • 1
    • 1
    人, 大鼠
    宿主
    • 114
    • 25
    • 3
    • 2
    • 1
    克隆类型
    • 116
    • 29
    多克隆
    标记
    • 51
    • 15
    • 9
    • 8
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD130/gp130 antibody is un-conjugated
    应用范围
    • 96
    • 38
    • 36
    • 30
    • 28
    • 25
    • 17
    • 13
    • 9
    • 9
    • 8
    • 6
    • 5
    • 4
    • 2
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    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 大鼠
    预测反应
    Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human gp130 around the phosphorylation site of Ser782
    亚型
    IgG
    Top Product
    Discover our top product IL6ST Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
    别名
    gp130 (IL6ST 产品)
    别名
    CD130 antibody, CDW130 antibody, GP130 antibody, IL-6RB antibody, 5133400A03Rik antibody, AA389424 antibody, BB405851 antibody, D13Ertd699e antibody, gp130 antibody, Ac1055 antibody, Gp130 antibody, Il-6rb antibody, IL-6 antibody, interleukin 6 signal transducer antibody, IL6ST antibody, Il6st antibody, il6st antibody
    背景

    Synonyms: gp130 phospho S782, gp130 phospho Ser782, p-gp130 Ser782, Interleukin-6 receptor subunit beta, IL-6R-beta, Interleukin-6 signal transducer, Membrane glycoprotein 130, gp130, CDw130, Oncostatin-M receptor subunit alpha, CD_antigen, CD130, GP130 RAPS, gp130 transducer chain, GP130-RAPS, IL6 ST, IL6R-beta, IL6ST.IL6R-beta, IL6RB_HUMAN, IL-6 receptor subunit beta, IL-6R subunit beta, IL-6RB.

    Background: CD130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.

    基因ID
    3572
    UniProt
    P40189
    途径
    JAK/STAT Signaling, Cellular Glucan Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Cancer Immune Checkpoints
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