TGFB1 蛋白
(Transforming Growth Factor, beta 1 (TGFB1))
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct 2009].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| TGFB1 Protein (AA 30-278) (Biotin,His-Avi Tag) | 人 | HEK-293 Cells |
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| TGFB1 Protein (AA 279-390) (AVI tag,Biotin) | 人 | HEK-293 Cells |
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| TGFB1 Protein (AA 30-278) (His tag) | 大鼠 | 大肠杆菌（E. Coli） |
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| TGFB1 Protein (AA 30-390, full length) (His-Myc tag) | 人 | Mammalian Cells |
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| TGFB1 Protein (AA 30-390, full length) (His-Avi Tag) | 小鼠 | Mammalian Cells |
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| TGFB1 Protein (AA 30-278) (His-Myc tag) | 人 | Mammalian Cells |
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| TGFB1 Protein (AA 1-390) (GST tag) | 人 | 小麦胚 |
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| TGFB1 Protein (AA 281-390) (GST tag) | 人 | 小麦胚 |
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| TGFB1 Protein (AA 279-390) (GST tag) | 人 | 小麦胚 |
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| TGFB1 Protein (AA 30-278) | 人 | HEK-293 Cells |
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| TGFB1 Protein (AA 279-390) (AVI tag,Biotin) | 人 | HEK-293 Cells |
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| TGFB1 Protein (AA 279-390) | 小鼠 | HEK-293 Cells |
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| TGFB1 Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| TGFB1 Protein (AA 30-278) (His tag,AVI tag,Biotin) | 人 | HEK-293 Cells |
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| TGFB1 Protein (AA 30-390) (His tag,AVI tag,Biotin) | 人 | HEK-293 Cells |
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| TGFB1 Protein (C33S) (His-Avi Tag,Biotin) | 人 | HEK-293 Cells |
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| TGFB1 Protein (AA 30-278, C33S) | 人 | 人细胞 |
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| TGFB1 Protein (AA 279-390) | 人 | CHO Cells |
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| TGFB1 Protein (AA 279-390) (AVI tag,Biotin) | 人 | 人细胞 |
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| TGFB1 Protein (AA 30-278, AA 279-390, N-Term) (Fc Tag) | 人, 小鼠 | CHO Cells |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by Bis-Tris PAGE
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 大鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- Greater than 95 % as determined by SDS-PAGE.
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 小鼠
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- Greater than 95 % as determined by SDS-PAGE.
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- Greater than 95 % as determined by SDS-PAGE.
Protein
- SDS (SDS-PAGE: 有验证图片)
- AP (Affinity Purification: 所列应用)
- AA (Antibody Array: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- 宿主
- 人
- 宿主
- 小麦胚
- 蛋白类型
- Recombinant
Protein
- SDS (SDS-PAGE: 有验证图片)
- AP (Affinity Purification: 所列应用)
- AA (Antibody Array: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- 宿主
- 人
- 宿主
- 小麦胚
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- CC (Cell Culture: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- CC (Cell Culture: 所列应用)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- WB (Western Blotting: 所列应用)
- 质量等级
- GMP Grade
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- >98 %
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % , as determined by SDS-PAGE and HPLC
Protein
- 宿主
- 人, 小鼠
- 宿主
- CHO Cells
- 蛋白类型
- Recombinant
- 纯度
- >98 % (SDS-PAGE)
- 生物活性
- Active
Latest Publications for our TGFB1 蛋白
: "Obesity reduces mammary epithelial cell TGFβ1 activity through macrophage-mediated extracellular matrix remodeling." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 34, Issue 6, pp. 8611-8624, (2020) (PubMed).
: "DHA inhibits Gremlin-1-induced epithelial-to-mesenchymal transition via ERK suppression in human breast cancer cells." in: Bioscience reports, Vol. 40, Issue 3, (2020) (PubMed).
: "Hydroxypropyl‑β‑cyclodextrin attenuates the epithelial‑to‑mesenchymal transition via endoplasmic reticulum stress in MDA‑MB‑231 breast cancer cells." in: Molecular medicine reports, Vol. 21, Issue 1, pp. 249-257, (2020) (PubMed).
: "Exosomal miR-532-5p from bone marrow mesenchymal stem cells reduce intervertebral disc degeneration by targeting RASSF5." in: Experimental cell research, Vol. 393, Issue 2, pp. 112109, (2020) (PubMed).
: "Sphingomyelin synthase 1 regulates the epithelial‑to‑mesenchymal transition mediated by the TGF‑β/Smad pathway in MDA‑MB‑231 cells." in: Molecular medicine reports, Vol. 19, Issue 2, pp. 1159-1167, (2019) (PubMed).
: "Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction." in: Molecular medicine reports, Vol. 19, Issue 4, pp. 3168-3178, (2019) (PubMed).
: "Periostin contributes to renal and cardiac dysfunction in rats with chronic kidney disease: Reduction of PPARα." in: Biochimie, Vol. 160, pp. 172-182, (2019) (PubMed).
: "Pioglitazone attenuates kidney fibrosis via miR-21-5p modulation." in: Life sciences, Vol. 232, pp. 116609, (2019) (PubMed).
: "ROCK Inhibitor Y27632 Induced Morphological Shift and Enhanced Neurite Outgrowth-Promoting Property of Olfactory Ensheathing Cells via YAP-Dependent Up-Regulation of L1-CAM." in: Frontiers in cellular neuroscience, Vol. 12, pp. 489, (2018) (PubMed).
: "Active Traction Force Response to Long-Term Cyclic Stretch Is Dependent on Cell Pre-stress." in: Biophysical journal, Vol. 110, Issue 8, pp. 1845-1857, (2017) (PubMed).
: "DHA inhibits Gremlin-1-induced epithelial-to-mesenchymal transition via ERK suppression in human breast cancer cells." in: Bioscience reports, Vol. 40, Issue 3, (2020) (PubMed).
: "Hydroxypropyl‑β‑cyclodextrin attenuates the epithelial‑to‑mesenchymal transition via endoplasmic reticulum stress in MDA‑MB‑231 breast cancer cells." in: Molecular medicine reports, Vol. 21, Issue 1, pp. 249-257, (2020) (PubMed).
: "Exosomal miR-532-5p from bone marrow mesenchymal stem cells reduce intervertebral disc degeneration by targeting RASSF5." in: Experimental cell research, Vol. 393, Issue 2, pp. 112109, (2020) (PubMed).
: "Sphingomyelin synthase 1 regulates the epithelial‑to‑mesenchymal transition mediated by the TGF‑β/Smad pathway in MDA‑MB‑231 cells." in: Molecular medicine reports, Vol. 19, Issue 2, pp. 1159-1167, (2019) (PubMed).
: "Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction." in: Molecular medicine reports, Vol. 19, Issue 4, pp. 3168-3178, (2019) (PubMed).
: "Periostin contributes to renal and cardiac dysfunction in rats with chronic kidney disease: Reduction of PPARα." in: Biochimie, Vol. 160, pp. 172-182, (2019) (PubMed).
: "Pioglitazone attenuates kidney fibrosis via miR-21-5p modulation." in: Life sciences, Vol. 232, pp. 116609, (2019) (PubMed).
: "ROCK Inhibitor Y27632 Induced Morphological Shift and Enhanced Neurite Outgrowth-Promoting Property of Olfactory Ensheathing Cells via YAP-Dependent Up-Regulation of L1-CAM." in: Frontiers in cellular neuroscience, Vol. 12, pp. 489, (2018) (PubMed).
: "Active Traction Force Response to Long-Term Cyclic Stretch Is Dependent on Cell Pre-stress." in: Biophysical journal, Vol. 110, Issue 8, pp. 1845-1857, (2017) (PubMed).
Aliases for TGFB1 蛋白
transforming growth factor beta 1 (TGFB1) 蛋白transforming growth factor beta-1 (TGFB1) 蛋白
transforming growth factor beta 1 (Tgfb1) 蛋白
transforming growth factor beta 1 L homeolog (tgfb1.L) 蛋白
transforming growth factor, beta 1 (Tgfb1) 蛋白
transforming growth factor, beta 1a (tgfb1a) 蛋白
transforming growth factor beta induced L homeolog (tgfbi.L) 蛋白
ai39657 蛋白
betaig-h3 蛋白
bigh3 蛋白
cdb1 蛋白
cdg2 蛋白
cdgg1 蛋白
CED 蛋白
ced 蛋白
csd 蛋白
csd1 蛋白
csd2 蛋白
csd3 蛋白
DPD1 蛋白
dpd1 蛋白
ebmd 蛋白
LAP 蛋白
lap 蛋白
lcd1 蛋白
TGF-beta 蛋白
tgf-beta 蛋白
TGF-BETA-1 蛋白
TGF-beta1 蛋白
TGF-beta5 蛋白
TGFB 蛋白
tgfb 蛋白
Tgfb 蛋白
Tgfb-1 蛋白
tgfb1 蛋白
TGFB1 蛋白
TGFB4 蛋白
tgfb5 蛋白
TGFbeta 蛋白
tgfbeta 蛋白
TGFbeta1 蛋白
wu:fb13a07 蛋白
xx:ai39657 蛋白
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