TGFBR2 蛋白
(Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| TGFBR2 Protein (AA 24-159) (mFc-Avi Tag) | 人 | HEK-293 Cells |
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| TGFBR2 Protein (AA 24-159) (hFc Tag) | 人 | HEK-293 Cells |
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| TGFBR2 Protein (AA 24-159) (mFc-Avi Tag,Biotin) | 人 | HEK-293 Cells |
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| TGFBR2 Protein (AA 23-159) (Fc Tag) | 人 | HEK-293 Cells |
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| TGFBR2 Protein (AA 23-166) (hIgG-His-tag) | 人 | Baculovirus infected Insect Cells |
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| TGFBR2 Protein (AA 24-159) (His tag) | 小鼠 | HEK-293 Cells |
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| TGFBR2 Protein (AA 1-166) (Fc Tag) | 大鼠 | HEK-293 Cells |
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| TGFBR2 Protein (AA 1-334) (GST tag) | 人 | 小麦胚 |
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| TGFBR2 Protein (AA 62-165) (GST tag) | 人 | 小麦胚 |
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| TGFBR2 Protein (AA 1-567) (GST tag) | 人 | 小麦胚 |
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| TGFBR2 Protein (AA 24-184) (Fc Tag) | 小鼠 | HEK-293 Cells |
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| TGFBR2 Protein (AA 23-159) (His tag,AVI tag,Biotin) | 人 | HEK-293 Cells |
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| TGFBR2 Protein (His-SUMO Tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| TGFBR2 Protein (GST tag,His tag) | 人 | 大肠杆菌（E. Coli） |
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| TGFBR2 Protein (AA 24-184, Isoform 2) (His-Fc tag) | 小鼠 | Mammalian Cells |
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| TGFBR2 Protein (GST tag) | 小鼠 | Baculovirus infected Insect Cells |
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| TGFBR2 Protein (GST tag) | 人 | Baculovirus infected Insect Cells |
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| TGFBR2 Protein (AA 24-184) (Fc Tag) | 小鼠 | HEK-293 Cells |
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| TGFBR2 Protein (AA 24-184) (Fc Tag) | 小鼠 | 人细胞 |
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| TGFBR2 Protein (Fc Tag,His tag) | 人 | HEK-293 Cells |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
Protein
- WB (Western Blotting: 有验证图片)
- CC (Cell Culture: 所列应用)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- 大鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- Imm (Immunogen: 所列应用)
- AcA (Activity Assay: 所列应用)
- 宿主
- 小鼠
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- >90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- 宿主
- 小鼠
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % by SDS-PAGE.
- 生物活性
- Active
Latest Publications for our TGFBR2 蛋白
: "Nicousamide protects kidney podocyte by inhibiting the TGFβ receptor II phosphorylation and AGE-RAGE signaling." in: American journal of translational research, Vol. 9, Issue 1, pp. 115-125, (2017) (PubMed).
: "Transforming growth factor ? induces expression of connective tissue growth factor in hepatic progenitor cells through Smad independent signaling." in: Cellular signalling, Vol. 25, Issue 10, pp. 1981-92, (2013) (PubMed).
: "Transforming growth factor ? induces expression of connective tissue growth factor in hepatic progenitor cells through Smad independent signaling." in: Cellular signalling, Vol. 25, Issue 10, pp. 1981-92, (2013) (PubMed).
Aliases for TGFBR2 蛋白
transforming growth factor beta receptor 2 (TGFBR2) 蛋白transforming growth factor, beta receptor II (Tgfbr2) 蛋白
transforming growth factor, beta receptor 2 (Tgfbr2) 蛋白
transforming growth factor beta receptor 2b (tgfbr2b) 蛋白
transforming growth factor beta receptor 2 (Tgfbr2) 蛋白
1110020H15Rik 蛋白
AAT3 蛋白
AU042018 蛋白
cb537 蛋白
DNIIR 蛋白
FAA3 蛋白
LDS1B 蛋白
LDS2B 蛋白
MFS2 蛋白
RIIC 蛋白
RIIDN 蛋白
TAAD2 蛋白
TBETA-RII 蛋白
TbetaR-II 蛋白
TbetaRII 蛋白
TBR-II 蛋白
TGF-beta 2 蛋白
TGFbeta-RII 蛋白
TGFBR2 蛋白
tgfbr2 蛋白
Tgfbr2T 蛋白
TGFBRII 蛋白
TGFR-2 蛋白
wu:fj05c10 蛋白
zgc:110498 蛋白
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