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TGFB1 产品

(Transforming Growth Factor, beta 1 (TGFB1))

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This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct 2009].

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Featured TGFB1 Categories

TGFB1 抗体

High quality antibodies with extensive validation data.

TGFB1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TGFB1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TGFB1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, ICC, IF
Validations
  • (5)
  • (11)
Cat. No. ABIN6266431
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7429469
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF
Validations
  • (6)
Cat. No. ABIN7217302
Quantity 100 μL
Datasheet Datasheet

Recommended TGFB1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (20)
  • (6)
Cat. No. ABIN6730882
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (14)
  • (2)
  • (1)
Cat. No. ABIN365402
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (28)
  • (1)
Cat. No. ABIN6960086
Quantity 96 tests
Datasheet Datasheet

Recommended TGFB1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275129
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275705
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
Cat. No. ABIN5569860
Quantity 5 μg
Datasheet Datasheet

Latest Publications for our TGFB1 Products

Yang, Lin, Yang, Liu, Fu, Liu, Tao, Huo, Zhang, Hua, Zhang, Li, Wang, Xue, Li, Sun: "Integrated genomic and transcriptomic analysis reveals unique characteristics of hepatic metastases and pro-metastatic role of complement C1q in pancreatic ductal adenocarcinoma." in: Genome biology, Vol. 22, Issue 1, pp. 4, (2022) (PubMed).

Passanha, Geuens, LaPointe: "Cadherin-11 influences differentiation in human mesenchymal stem cells by regulating the extracellular matrix via the TGFβ1 pathway." in: Stem cells (Dayton, Ohio), (2022) (PubMed).

Liu, Bell, Herrmann, Arnhold, Mercieca, Anders, Nagel-Wolfrum, Thanos, Prokosch: "Crystallins Play a Crucial Role in Glaucoma and Promote Neuronal Cell Survival in an In Vitro Model Through Modulating Müller Cell Secretion." in: Investigative ophthalmology & visual science, Vol. 63, Issue 8, pp. 3, (2022) (PubMed).

Yan, Liu, Dou, Xu, Yan: "Soufeng Yuchuan decoction mitigates the ovalbumin-induced lung damage in a rat model of asthma." in: Biomedicine & pharmacotherapy, Vol. 125, pp. 109933, (2021) (PubMed).

Wu, He, Wang, Liang, Zhang, Liang, Chen: "Dahuang Zhechong Pills Suppress Silicosis Fibrosis Progression via p38 MAPK/TGF-β1/Smad Pathway In Vitro." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2021, pp. 6662261, (2021) (PubMed).

Chamberlin, Thompson, Hillers-Ziemer, Walton, Arendt: "Obesity reduces mammary epithelial cell TGFβ1 activity through macrophage-mediated extracellular matrix remodeling." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 34, Issue 6, pp. 8611-8624, (2020) (PubMed).

Sung, Kim, Bae, Jo, Park: "DHA inhibits Gremlin-1-induced epithelial-to-mesenchymal transition via ERK suppression in human breast cancer cells." in: Bioscience reports, Vol. 40, Issue 3, (2020) (PubMed).

Wu, Zhao, He, He, Wang, Wan, Chen, Yan: "Hydroxypropyl‑β‑cyclodextrin attenuates the epithelial‑to‑mesenchymal transition via endoplasmic reticulum stress in MDA‑MB‑231 breast cancer cells." in: Molecular medicine reports, Vol. 21, Issue 1, pp. 249-257, (2020) (PubMed).

Guo, Zhu, Liu, Ge, Jiang, Zhao: "Hyperoside protects against heart failure-induced liver fibrosis in rats." in: Acta histochemica, Vol. 121, Issue 7, pp. 804-811, (2020) (PubMed).

Chi, Feng, Shang, Jiao, Sun, Jiang, Meng, Fan, Lin, Zhong, Yang: "Circulating Connective Tissue Growth Factor Is Associated with Diastolic Dysfunction in Patients with Diastolic Heart Failure." in: Cardiology, Vol. 143, Issue 3-4, pp. 77-84, (2020) (PubMed).

Synonyms and alternative names related to TGFB1

transforming growth factor beta 1 (TGFB1), transforming growth factor beta-1 (TGFB1), transforming growth factor beta 1 (Tgfb1), transforming growth factor beta 1 L homeolog (tgfb1.L), transforming growth factor, beta 1 (Tgfb1), transforming growth factor, beta 1a (tgfb1a), transforming growth factor beta induced L homeolog (tgfbi.L), ai39657, betaig-h3, bigh3, cdb1, cdg2, cdgg1, CED, ced, csd, csd1, csd2, csd3, DPD1, dpd1, ebmd, LAP, lap, lcd1, TGF-beta, tgf-beta, TGF-BETA-1, TGF-beta1, TGF-beta5, TGFB, tgfb, Tgfb, Tgfb-1, tgfb1, TGFB1, TGFB4, tgfb5, TGFbeta, tgfbeta, TGFbeta1, wu:fb13a07, xx:ai39657

Protein level used designations for TGFB1

  • TGF-beta 1 protein
  • TGF-beta-1
  • latency-associated peptide
  • transforming growth factor beta-1
  • transforming growth factor, beta 1 (Camurati-Engelmann disease)
  • transforming growth factor-beta 1
  • transforming growth factor beta 1
  • transforming growth factor-beta
  • transforming growth factor beta1
  • transforming growth factor-beta-1
  • TGF-beta-5
  • tgf beta
  • tgf-beta 5
  • transforming gorwth factor-Beta5
  • transforming growth factor-B5
  • transforming growth factor-beta 5
  • TGF-beta 1
  • regulatory protein
  • transforming growth factor, beta-1
  • transforming growth factor, beta 1
  • transforming growth factor, beta-induced, 68kDa
  • transforming growth factor beta-1-like
  • transforming growth factor beta 4
  • TGF beta
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