TNFRSF4 蛋白
(Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| TNFRSF4 Protein (AA 29-214) (His tag,Fc Tag) | 人 | HEK-293 Cells |
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| TNFRSF4 Protein (AA 20-211) (Biotin,His-Avi Tag) | 小鼠 | HEK-293 Cells |
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| TNFRSF4 Protein (AA 20-211) (His-Avi Tag) | 小鼠 | HEK-293 Cells |
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| TNFRSF4 Protein (AA 29-216) (His-Avi Tag) | 人 | HEK-293 Cells |
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| TNFRSF4 Protein (AA 29-216) (Biotin,His-Avi Tag) | 人 | HEK-293 Cells |
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| TNFRSF4 Protein (AA 29-216) (His tag) | 人 | HEK-293 Cells |
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| TNFRSF4 Protein (AA 29-216) (hFc Tag,Biotin) | 人 | HEK-293 Cells |
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| TNFRSF4 Protein (AA 29-214) (hIgG-His-tag) | 人 | Baculovirus infected Insect Cells |
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| TNFRSF4 Protein (AA 20-211) (hFc Tag) | 小鼠 | Mammalian Cells |
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| TNFRSF4 Protein (AA 28-214) (His tag) | Cynomolgus | HEK-293 Cells |
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| TNFRSF4 Protein (AA 31-130) (GST tag) | 人 | 小麦胚 |
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| TNFRSF4 Protein (AA 20-211) (His tag) | 小鼠 | HEK-293 Cells |
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| TNFRSF4 Protein (AA 29-216) (His tag,AVI tag,Biotin) | 人 | HEK-293 Cells |
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| TNFRSF4 Protein (AA 20-211) (His-Fc tag) | 小鼠 | Mammalian Cells |
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| TNFRSF4 Protein (AA 29-216) (mFc Tag) | 人 | 人细胞 |
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| TNFRSF4 Protein (His tag) | 小鼠 | HEK-293 Cells |
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| TNFRSF4 Protein (AA 29-216, C-Term) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| TNFRSF4 Protein (AA 29-216, Extracellular Domain, N-Term) (Fc Tag) | 人 | HEK-293 Cells |
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| TNFRSF4 Protein (AA 20-211, Extracellular Domain, N-Term) (Fc Tag) | 小鼠 | HEK-293 Cells |
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| TNFRSF4 Protein (His-Avi Tag,Biotin) | 人 | HEK-293 Cells |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- Bind (Binding Studies: 有验证图片)
3 references - 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 小鼠
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- BLI (Bio-Layer Interferometry: 所列应用)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- Imm (Immunogen: 所列应用)
- AcA (Activity Assay: 所列应用)
- 宿主
- 小鼠
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- >90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- >97 % (SDS-PAGE)
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >98 % (SDS-PAGE)
- 生物活性
- Active
Protein
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >98 % (SDS-PAGE)
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % , as determined by SDS-PAGE and HPLC
Latest Publications for our TNFRSF4 蛋白
: "Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist." in: Journal for immunotherapy of cancer, Vol. 9, Issue 1, (2021) (PubMed).
: "Affinity maturation of antibodies by combinatorial codon mutagenesis versus error-prone PCR." in: mAbs, Vol. 12, Issue 1, pp. 1803646, (2020) (PubMed).
: "Agonist redirected checkpoint, PD1-Fc-OX40L, for cancer immunotherapy." in: Journal for immunotherapy of cancer, Vol. 6, Issue 1, pp. 149, (2018) (PubMed).
: "Affinity maturation of antibodies by combinatorial codon mutagenesis versus error-prone PCR." in: mAbs, Vol. 12, Issue 1, pp. 1803646, (2020) (PubMed).
: "Agonist redirected checkpoint, PD1-Fc-OX40L, for cancer immunotherapy." in: Journal for immunotherapy of cancer, Vol. 6, Issue 1, pp. 149, (2018) (PubMed).
Aliases for TNFRSF4 蛋白
TNF receptor superfamily member 4 (TNFRSF4) 蛋白tumor necrosis factor receptor superfamily, member 4 (Tnfrsf4) 蛋白
TNF receptor superfamily member 4 (Tnfrsf4) 蛋白
ACT35 蛋白
CD134 蛋白
Ly-70 蛋白
Ox40 蛋白
OX40 蛋白
TNFRSF4 蛋白
Txgp1 蛋白
TXGP1L 蛋白
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