TNF alpha 蛋白
(Tumor Necrosis Factor alpha (TNF alpha))
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| TNF alpha Protein (AA 77-233) (Biotin,His-Avi Tag) | 人 | HEK-293 Cells |
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| TNF alpha Protein (AA 78-233) (His tag) | 人 | HEK-293 Cells |
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| TNF alpha Protein (AA 77-233) (His-Avi Tag) | 人 | HEK-293 Cells |
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| TNF alpha Protein (AA 78-235) | 兔 | 大肠杆菌（E. Coli） |
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| TNF alpha Protein (AA 1-233) (GST tag) | 人 | 小麦胚 |
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| TNF alpha Protein (AA 89-235) | 小鼠 | 大肠杆菌（E. Coli） |
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| TNF alpha Protein (AA 77-233) (Biotin) | 人 | HEK-293 Cells |
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| TNF alpha Protein (AA 77-233) (His tag,AVI tag,Biotin) | 人 | HEK-293 Cells |
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| TNF alpha Protein (AA 77-233) | 人 | HEK-293 Cells |
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| TNF alpha Protein (AA 80-235) (His tag) | 大鼠 | Mammalian Cells |
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| TNF alpha Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| TNF alpha Protein (AA 84-235) | 小鼠 | Yeast (Pichia pastoris) |
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| TNF alpha 蛋白 | 人 | Yeast (Pichia pastoris) |
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| TNF alpha Protein (AA 77-233) (His tag) | 犬 | 大肠杆菌（E. Coli） |
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| TNF alpha Protein (AA 80-234) (His tag) | 豚鼠 | 大肠杆菌（E. Coli） |
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| TNF alpha Protein (AA 80-235) (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| TNF alpha Protein (AA 78-232) (His tag) | Pig | 大肠杆菌（E. Coli） |
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| TNF alpha Protein (AA 80-235) (His tag) | 大鼠 | 大肠杆菌（E. Coli） |
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| TNF alpha Protein (AA 80-235) (His tag) | 小鼠 | Baculovirus infected Insect Cells |
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| TNF alpha Protein (full length) | 人 | 大肠杆菌（E. Coli） |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- CC (Cell Culture: 所列应用)
- 宿主
- 兔
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- AP (Affinity Purification: 所列应用)
- AA (Antibody Array: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
3 references - 宿主
- 人
- 宿主
- 小麦胚
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- CC (Cell Culture: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- Bind (Binding Studies: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by reduced SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- Bind (Binding Studies: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- Bind (Binding Studies: 有验证图片)
- 质量等级
- HPLC verified
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- AcA (Activity Assay: 有验证图片)
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 大鼠
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- >90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 95 % as determined by reducing SDS-PAGE.
Protein
- 宿主
- 小鼠
- 宿主
- Yeast (Pichia pastoris)
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as analyzed by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- Yeast (Pichia pastoris)
- 纯度
- > 97 % by SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 犬
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 豚鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- Pig
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 大鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- AcA (Activity Assay: 所列应用)
- 宿主
- 小鼠
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 98 % pure
- 生物活性
- Active
Latest Publications for our TNF alpha 蛋白
: "Dual-optofluidic waveguide in-line fiber biosensor for real-time label-free detection of interferon-gamma with temperature compensation." in: Optics express, Vol. 28, Issue 7, pp. 10491-10504, (2021) (PubMed).
: "Identification of Human Single-Domain Antibodies against SARS-CoV-2." in: Cell host & microbe, (2020) (PubMed).
: "Sex Differences in Rat Intervertebral Disc Structure and Function Following Annular Puncture Injury." in: Spine, Vol. 44, Issue 18, pp. 1257-1269, (2020) (PubMed).
: "Peroxisome proliferator-activated receptor gamma as a theragnostic target for mesenchymal-type glioblastoma patients." in: Experimental & molecular medicine, Vol. 52, Issue 4, pp. 629-642, (2020) (PubMed).
: "Decrease of MiR-31 induced by TNF-α inhibitor activates SATB2/RUNX2 pathway and promotes osteogenic differentiation in ethanol-induced osteonecrosis." in: Journal of cellular physiology, Vol. 234, Issue 4, pp. 4314-4326, (2019) (PubMed).
: "Overexpression of microRNA-590-3p promotes the proliferation of and inhibits the apoptosis of myocardial cells through inhibition of the NF-κB signaling pathway by binding to RIPK1." in: Journal of cellular biochemistry, Vol. 120, Issue 3, pp. 3559-3573, (2019) (PubMed).
: "MAbTope: A Method for Improved Epitope Mapping." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 201, Issue 10, pp. 3096-3105, (2019) (PubMed).
: "Glutaminase C Regulates Microglial Activation and Pro-inflammatory Exosome Release: Relevance to the Pathogenesis of Alzheimer's Disease." in: Frontiers in cellular neuroscience, Vol. 13, pp. 264, (2019) (PubMed).
: "The N-terminal ubiquitin-associated domain of Cezanne is crucial for its function to suppress NF-κB pathway." in: Journal of cellular biochemistry, Vol. 119, Issue 2, pp. 1979-1991, (2018) (PubMed).
: "Surrogate potency assays: Comparison of binding profiles complements dose response curves for unambiguous assessment of relative potencies." in: Journal of pharmaceutical analysis, Vol. 8, Issue 2, pp. 138-146, (2018) (PubMed).
: "Identification of Human Single-Domain Antibodies against SARS-CoV-2." in: Cell host & microbe, (2020) (PubMed).
: "Sex Differences in Rat Intervertebral Disc Structure and Function Following Annular Puncture Injury." in: Spine, Vol. 44, Issue 18, pp. 1257-1269, (2020) (PubMed).
: "Peroxisome proliferator-activated receptor gamma as a theragnostic target for mesenchymal-type glioblastoma patients." in: Experimental & molecular medicine, Vol. 52, Issue 4, pp. 629-642, (2020) (PubMed).
: "Decrease of MiR-31 induced by TNF-α inhibitor activates SATB2/RUNX2 pathway and promotes osteogenic differentiation in ethanol-induced osteonecrosis." in: Journal of cellular physiology, Vol. 234, Issue 4, pp. 4314-4326, (2019) (PubMed).
: "Overexpression of microRNA-590-3p promotes the proliferation of and inhibits the apoptosis of myocardial cells through inhibition of the NF-κB signaling pathway by binding to RIPK1." in: Journal of cellular biochemistry, Vol. 120, Issue 3, pp. 3559-3573, (2019) (PubMed).
: "MAbTope: A Method for Improved Epitope Mapping." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 201, Issue 10, pp. 3096-3105, (2019) (PubMed).
: "Glutaminase C Regulates Microglial Activation and Pro-inflammatory Exosome Release: Relevance to the Pathogenesis of Alzheimer's Disease." in: Frontiers in cellular neuroscience, Vol. 13, pp. 264, (2019) (PubMed).
: "The N-terminal ubiquitin-associated domain of Cezanne is crucial for its function to suppress NF-κB pathway." in: Journal of cellular biochemistry, Vol. 119, Issue 2, pp. 1979-1991, (2018) (PubMed).
: "Surrogate potency assays: Comparison of binding profiles complements dose response curves for unambiguous assessment of relative potencies." in: Journal of pharmaceutical analysis, Vol. 8, Issue 2, pp. 138-146, (2018) (PubMed).
Aliases for TNF alpha 蛋白
tumor necrosis factor (TNF) 蛋白tumor necrosis factor (Tnf) 蛋白
tumor necrosis factor (tnf) 蛋白
tumor necrosis factor b (TNF superfamily, member 2) (tnfb) 蛋白
tumor necrosis factor alpha (tnf-alpha) 蛋白
tumor necrosis factor (LOC103694380) 蛋白
tumor necrosis factor a (TNF superfamily, member 2) (tnfa) 蛋白
Cachectin 蛋白
cTNF 蛋白
DIF 蛋白
dif 蛋白
RATTNF 蛋白
tnf 蛋白
TNF-a 蛋白
TNF-alpha 蛋白
Tnf-alpha 蛋白
TNF-ALPHA 蛋白
tnf-alpha 蛋白
TNFA 蛋白
Tnfa 蛋白
TNFa 蛋白
tnfa 蛋白
tnfa-like 蛋白
TNFalpha 蛋白
Tnfsf1a 蛋白
TNFSF2 蛋白
tnfsf2 蛋白
xtnf 蛋白
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