TNKS 蛋白
(Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS))
Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates poly-ADP-ribosylation of TERF1, thereby contributing to the regulation of telomere length. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles.
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4 results
custom-made
TNKS
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
TNKS
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 97 %
SDS, WB, Imm, PC
custom-made
TNKS
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
Aliases for TNKS 蛋白
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b (tnksb) 蛋白tankyrase (TNKS) 蛋白
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase (Tnks) 蛋白
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 S homeolog (tnks2.S) 蛋白
tankyrase (Tnks) 蛋白
4930554K12Rik 蛋白
AI662855 蛋白
ARTD5 蛋白
C86528 蛋白
D130072O21Rik 蛋白
mTNKS1 蛋白
PARP-5a 蛋白
PARP5A 蛋白
PARPL 蛋白
pART5 蛋白
TANK1 蛋白
tankyrase-1 蛋白
TIN1 蛋白
TINF1 蛋白
TNKS1 蛋白
wu:fe02c12 蛋白
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