HLA-ABC 抗体
(HLA-ABC)
HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| HLA-ABC 抗体 (PE) | 人, Cow, Baboon, Cynomolgus, 猕猴, Macaque, Shrew, Chimpanzee, Gorilla | 小鼠 Monoclonal |
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| HLA-ABC 抗体 | 人, Cow, Baboon, Cat, 猴 | 小鼠 Monoclonal |
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| HLA-ABC 抗体 | 人, 小鼠, Non-Human Primate | 小鼠 Monoclonal |
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| HLA-ABC 抗体 (PE) | 人, Baboon, Cynomolgus, 猕猴 | 小鼠 Monoclonal |
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| HLA-ABC 抗体 (FITC) | 人, Baboon, Cynomolgus, 猕猴 | 小鼠 Monoclonal |
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| HLA-ABC 抗体 | 人, Baboon, Cynomolgus, 猕猴 | 小鼠 Monoclonal |
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| HLA-ABC 抗体 (APC) | 人, Baboon, Cynomolgus, 猕猴 | 小鼠 Monoclonal |
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| HLA-ABC 抗体 | 人, Cow, Baboon, Cynomolgus, 猕猴, Macaque, Shrew, Chimpanzee, Gorilla | 小鼠 Monoclonal |
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| HLA-ABC 抗体 | 人, Cow, Baboon, Cynomolgus, 猕猴, Macaque, Shrew, Chimpanzee, Gorilla | 小鼠 Monoclonal |
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| HLA-ABC 抗体 (HRP) | 人, Cow, Baboon, Cynomolgus, 猕猴, Macaque, Shrew, Chimpanzee, Gorilla | 小鼠 Monoclonal |
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| HLA-ABC 抗体 (Biotin) | 人, Cow, Baboon, Cynomolgus, 猕猴, Macaque, Shrew, Chimpanzee, Gorilla | 小鼠 Monoclonal |
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| HLA-ABC 抗体 (FITC) | 人, Cow, Baboon, Cynomolgus, 猕猴, Macaque, Shrew, Chimpanzee, Gorilla | 小鼠 Monoclonal |
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| HLA-ABC 抗体 | 人 | 大鼠 Monoclonal |
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| HLA-ABC 抗体 | 人, Cow | 小鼠 Monoclonal |
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| HLA-ABC 抗体 (FITC) | 人, Cow, Baboon, Cynomolgus, 猕猴, Macaque, Shrew | 小鼠 Monoclonal |
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| HLA-ABC 抗体 | 人 | 大鼠 Monoclonal |
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| HLA-ABC 抗体 (Biotin) | 人, Cow, Baboon, Cynomolgus, 猕猴, Macaque, Shrew | 小鼠 Monoclonal |
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| HLA-ABC 抗体 | 人, Cow, Baboon, Macaque, Cat, 猴, 灵长类, Chimpanzee | 小鼠 Monoclonal |
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| HLA-ABC 抗体 | 人, Cow, Cat, 猴, 灵长类 | 小鼠 Monoclonal |
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| Recombinant HLA-ABC 抗体 | 人 | 小鼠 Monoclonal |
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Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
3 references - 适用
- 人, Cow, Baboon, Cynomolgus, 猕猴, Macaque, Shrew, Chimpanzee, Gorilla
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- W6-32
- 标记
- PE
- 抗体亚型
- IgG2a
Primary Antibody
- FACS (Flow Cytometry: 所列应用)
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, Cow, Baboon, Cat, 猴
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- W6-32
- 标记
- unconjugated
- 抗体亚型
- IgG2a kappa
Primary Antibody
- SDS (SDS-PAGE: 有验证图片)
- FACS (Flow Cytometry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠, Non-Human Primate
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 246-B8-E7
- 标记
- unconjugated
- 抗体亚型
- IgG2a, kappa
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- 质量等级
- GMP Grade
- 适用
- 人, Baboon, Cynomolgus, 猕猴
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- W6-32
- 标记
- PE
- 抗体亚型
- IgG2a, kappa
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- 质量等级
- GMP Grade
- 适用
- 人, Baboon, Cynomolgus, 猕猴
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- W6-32
- 标记
- FITC
- 抗体亚型
- IgG2a, kappa
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- 质量等级
- GMP Grade
- 适用
- 人, Baboon, Cynomolgus, 猕猴
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- W6-32
- 标记
- unconjugated
- 抗体亚型
- IgG2a, kappa
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- 质量等级
- GMP Grade
- 适用
- 人, Baboon, Cynomolgus, 猕猴
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- W6-32
- 标记
- APC
- 抗体亚型
- IgG2a, kappa
Primary Antibody
- FACS (Flow Cytometry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- IP (Immunoprecipitation: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, Cow, Baboon, Cynomolgus, 猕猴, Macaque, Shrew, Chimpanzee, Gorilla
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- W6-32
- 标记
- unconjugated
- 抗体亚型
- IgG2a
Primary Antibody
- FACS (Flow Cytometry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- IP (Immunoprecipitation: 所列应用)
- ELISA (ELISA: 所列应用)
- Func (Functional Studies: 所列应用)
- 适用
- 人, Cow, Baboon, Cynomolgus, 猕猴, Macaque, Shrew, Chimpanzee, Gorilla
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- W6-32
- 标记
- unconjugated
- 抗体亚型
- IgG2a
Primary Antibody
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人, Cow, Baboon, Cynomolgus, 猕猴, Macaque, Shrew, Chimpanzee, Gorilla
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- W6-32
- 标记
- HRP
- 抗体亚型
- IgG2a
Primary Antibody
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, Cow, Baboon, Cynomolgus, 猕猴, Macaque, Shrew, Chimpanzee, Gorilla
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- W6-32
- 标记
- Biotin
- 抗体亚型
- IgG2a
Primary Antibody
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, Cow, Baboon, Cynomolgus, 猕猴, Macaque, Shrew, Chimpanzee, Gorilla
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- W6-32
- 标记
- FITC
- 抗体亚型
- IgG2a
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- IF (Immunofluorescence: 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- IP (Immunoprecipitation: 所列应用)
- Func (Functional Studies: 所列应用)
- 适用
- 人
- 宿主
- 大鼠
- 克隆形成能力
- Monoclonal
- 克隆
- YTH862-2
- 标记
- unconjugated
- 抗体亚型
- IgG2b
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- FACS (Flow Cytometry: 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- IP (Immunoprecipitation: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, Cow
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- MEM-123
- 标记
- unconjugated
- 抗体亚型
- IgG3
Primary Antibody
- IF (Immunofluorescence: 有验证图片)
- FACS (Flow Cytometry: 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- IP (Immunoprecipitation: 所列应用)
- Func (Functional Studies: 所列应用)
- EIA (Enzyme Immunoassay: 所列应用)
- DNA Mic (DNA Microscopy: 所列应用)
- 适用
- 人, Cow, Baboon, Macaque, Cat, 猴, 灵长类, Chimpanzee
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- W6-32
- 标记
- unconjugated
- 抗体亚型
- IgG2a
Primary Antibody
- FACS (Flow Cytometry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- IP (Immunoprecipitation: 所列应用)
- EIA (Enzyme Immunoassay: 所列应用)
- 适用
- 人, Cow, Cat, 猴, 灵长类
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- W6-32
- 标记
- unconjugated
- 抗体亚型
- IgG2a
Primary Antibody
- ELISA (ELISA: 所列应用)
- Func (Functional Studies: 所列应用)
- IGA (Immunogenicity Assay: 所列应用)
- Neut (Neutralization: 所列应用)
- 质量等级
- In vivo Grade
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- W6-32
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG2a
Latest Publications for our HLA-ABC 抗体
: "Strong Replication Interference Between Hepatitis Delta Viruses in Human Liver Chimeric Mice." in: Frontiers in microbiology, Vol. 12, pp. 671466, (2021) (PubMed).
: "Collagen VII Expression Is Required in Both Keratinocytes and Fibroblasts for Anchoring Fibril Formation in Bilayer Engineered Skin Substitutes." in: Cell transplantation, Vol. 28, Issue 9-10, pp. 1242-1256, (2020) (PubMed).
: "Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo. ..." in: Neuron, (2019) (PubMed).
: "Human embryonic stem cell derived-mesenchymal stem cells: an alternative mesenchymal stem cell source for regenerative medicine therapy." in: Regenerative medicine, Vol. 9, Issue 4, pp. 453-65, (2014) (PubMed).
: "Heterelogous expression of mutated HLA-G decreases immunogenicity of human embryonic stem cells and their epidermal derivatives." in: Stem cell research, Vol. 13, Issue 2, pp. 342-54, (2014) (PubMed).
: "HLA class I allelic sequence and conformation regulate leukocyte Ig-like receptor binding." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 5, pp. 2990-7, (2011) (PubMed).
: "The Epstein-Barr virus-encoded BILF1 protein modulates immune recognition of endogenously processed antigen by targeting major histocompatibility complex class I molecules trafficking on both the ..." in: Journal of virology, Vol. 85, Issue 4, pp. 1604-14, (2011) (PubMed).
: "Viral inhibition assay: a CD8 T cell neutralization assay for use in clinical trials of HIV-1 vaccine candidates." in: The Journal of infectious diseases, Vol. 201, Issue 5, pp. 720-9, (2010) (PubMed).
: "The nature of peptides presented by an HLA class I low expression allele." in: Haematologica, Vol. 95, Issue 8, pp. 1373-80, (2010) (PubMed).
: "WT1 peptide vaccination in combination with imatinib therapy for a patient with CML in the chronic phase." in: International journal of medical sciences, Vol. 7, Issue 2, pp. 72-81, (2010) (PubMed).
: "Collagen VII Expression Is Required in Both Keratinocytes and Fibroblasts for Anchoring Fibril Formation in Bilayer Engineered Skin Substitutes." in: Cell transplantation, Vol. 28, Issue 9-10, pp. 1242-1256, (2020) (PubMed).
: "Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo. ..." in: Neuron, (2019) (PubMed).
: "Human embryonic stem cell derived-mesenchymal stem cells: an alternative mesenchymal stem cell source for regenerative medicine therapy." in: Regenerative medicine, Vol. 9, Issue 4, pp. 453-65, (2014) (PubMed).
: "Heterelogous expression of mutated HLA-G decreases immunogenicity of human embryonic stem cells and their epidermal derivatives." in: Stem cell research, Vol. 13, Issue 2, pp. 342-54, (2014) (PubMed).
: "HLA class I allelic sequence and conformation regulate leukocyte Ig-like receptor binding." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 5, pp. 2990-7, (2011) (PubMed).
: "The Epstein-Barr virus-encoded BILF1 protein modulates immune recognition of endogenously processed antigen by targeting major histocompatibility complex class I molecules trafficking on both the ..." in: Journal of virology, Vol. 85, Issue 4, pp. 1604-14, (2011) (PubMed).
: "Viral inhibition assay: a CD8 T cell neutralization assay for use in clinical trials of HIV-1 vaccine candidates." in: The Journal of infectious diseases, Vol. 201, Issue 5, pp. 720-9, (2010) (PubMed).
: "The nature of peptides presented by an HLA class I low expression allele." in: Haematologica, Vol. 95, Issue 8, pp. 1373-80, (2010) (PubMed).
: "WT1 peptide vaccination in combination with imatinib therapy for a patient with CML in the chronic phase." in: International journal of medical sciences, Vol. 7, Issue 2, pp. 72-81, (2010) (PubMed).
Aliases for HLA-ABC 抗体
major histocompatibility complex, class I, A (HLA-A) 抗体HLAA 抗体
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