LAG3 蛋白
(Lymphocyte-Activation Gene 3 (LAG3))
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| LAG3 Protein (AA 23-434) (Biotin,His-Avi Tag) | 人 | HEK-293 Cells |
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| LAG3 Protein (AA 23-450) (hFc Tag) | 人 | HEK-293 Cells |
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| LAG3 Protein (AA 23-450) (His tag) | 人 | HEK-293 Cells |
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| LAG3 Protein (Fc Tag) | 人, 小鼠, 猴 | CHO Cells |
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| LAG3 Protein (AA 23-450) (Fc Tag) | 人 | HEK-293 Cells |
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| LAG3 Protein (AA 23-222) (His-IF2DI Tag) | 人 | 大肠杆菌（E. Coli） |
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| LAG3 Protein (AA 23-450) (His tag) | Cynomolgus | HEK-293 Cells |
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| LAG3 Protein (AA 1-442) (His tag) | 大鼠 | HEK-293 Cells |
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| LAG3 Protein (AA 18-449) (Fc Tag) | Cynomolgus | HEK-293 Cells |
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| LAG3 Protein (AA 1-360) (GST tag) | 人 | 小麦胚 |
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| LAG3 Protein (AA 23-442) (His tag) | 小鼠 | HEK-293 Cells |
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| LAG3 Protein (AA 18-449) (Fc Tag) | Cynomolgus | HEK-293 Cells |
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| LAG3 Protein (AA 23-450) (His tag) | 人 | HEK-293 Cells |
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| LAG3 Protein (AA 23-450) (mFc Tag) | 人 | 人细胞 |
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| LAG3 Protein (AA 23-450) (Fc Tag) | 人 | 人细胞 |
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| LAG3 Protein (AA 23-442) (Fc Tag) | 小鼠 | 人细胞 |
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| LAG3 Protein (AA 23-442) (mFc Tag) | 小鼠 | 人细胞 |
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| LAG3 Protein (AA 23-450) (mFc Tag) | 人 | 人细胞 |
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| LAG3 Protein (AA 18-449, Pro74) (Fc Tag) | Cynomolgus | 人细胞 |
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| LAG3 Protein (His-Avi Tag,Biotin) | 人 | HEK-293 Cells |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- SDS (SDS-PAGE: 所列应用)
- FACS (Flow Cytometry: 所列应用)
6 references - 宿主
- 人, 小鼠, 猴
- 宿主
- CHO Cells
- 蛋白类型
- Recombinant
- 纯度
- >99 % (SDS-PAGE)
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- 大鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- Bind (Binding Studies: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % , as determined by SDS-PAGE and HPLC
Latest Publications for our LAG3 蛋白
: "Peptide-based PET tracer targeting LAG-3 for evaluating the efficacy of immunotherapy in melanoma." in: Journal for immunotherapy of cancer, Vol. 12, Issue 7, (2024) (PubMed).
: "Characterization of a novel anti-human lymphocyte activation gene 3 (LAG-3) antibody for cancer immunotherapy." in: mAbs, Vol. 11, Issue 6, pp. 1139-1148, (2019) (PubMed).
: "A signal-decreased electrochemical immunosensor for the sensitive detection of LAG-3 protein based on a hollow nanobox-MOFs/AuPt alloy." in: Biosensors & bioelectronics, Vol. 113, pp. 148-156, (2018) (PubMed).
: "A soluble form of lymphocyte activation gene-3 (IMP321) induces activation of a large range of human effector cytotoxic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 6, pp. 4202-11, (2007) (PubMed).
: "A soluble lymphocyte activation gene-3 (sLAG-3) protein as a prognostic factor in human breast cancer expressing estrogen or progesterone receptors." in: Cancer letters, Vol. 235, Issue 1, pp. 147-53, (2006) (PubMed).
: "LAG-3 (CD223) reduces macrophage and dendritic cell differentiation from monocyte precursors." in: Immunology, Vol. 114, Issue 3, pp. 369-74, (2005) (PubMed).
: "LAG-3 enables DNA vaccination to persistently prevent mammary carcinogenesis in HER-2/neu transgenic BALB/c mice." in: Cancer research, Vol. 63, Issue 10, pp. 2518-25, (2003) (PubMed).
: "Maturation and activation of dendritic cells induced by lymphocyte activation gene-3 (CD223)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 8, pp. 3874-80, (2002) (PubMed).
: "T cell major histocompatibility complex class II molecules down-regulate CD4+ T cell clone responses following LAG-3 binding." in: European journal of immunology, Vol. 26, Issue 5, pp. 1180-6, (1996) (PubMed).
: "CD4/major histocompatibility complex class II interaction analyzed with CD4- and lymphocyte activation gene-3 (LAG-3)-Ig fusion proteins." in: European journal of immunology, Vol. 25, Issue 9, pp. 2718-21, (1995) (PubMed).
: "Characterization of a novel anti-human lymphocyte activation gene 3 (LAG-3) antibody for cancer immunotherapy." in: mAbs, Vol. 11, Issue 6, pp. 1139-1148, (2019) (PubMed).
: "A signal-decreased electrochemical immunosensor for the sensitive detection of LAG-3 protein based on a hollow nanobox-MOFs/AuPt alloy." in: Biosensors & bioelectronics, Vol. 113, pp. 148-156, (2018) (PubMed).
: "A soluble form of lymphocyte activation gene-3 (IMP321) induces activation of a large range of human effector cytotoxic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 6, pp. 4202-11, (2007) (PubMed).
: "A soluble lymphocyte activation gene-3 (sLAG-3) protein as a prognostic factor in human breast cancer expressing estrogen or progesterone receptors." in: Cancer letters, Vol. 235, Issue 1, pp. 147-53, (2006) (PubMed).
: "LAG-3 (CD223) reduces macrophage and dendritic cell differentiation from monocyte precursors." in: Immunology, Vol. 114, Issue 3, pp. 369-74, (2005) (PubMed).
: "LAG-3 enables DNA vaccination to persistently prevent mammary carcinogenesis in HER-2/neu transgenic BALB/c mice." in: Cancer research, Vol. 63, Issue 10, pp. 2518-25, (2003) (PubMed).
: "Maturation and activation of dendritic cells induced by lymphocyte activation gene-3 (CD223)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 8, pp. 3874-80, (2002) (PubMed).
: "T cell major histocompatibility complex class II molecules down-regulate CD4+ T cell clone responses following LAG-3 binding." in: European journal of immunology, Vol. 26, Issue 5, pp. 1180-6, (1996) (PubMed).
: "CD4/major histocompatibility complex class II interaction analyzed with CD4- and lymphocyte activation gene-3 (LAG-3)-Ig fusion proteins." in: European journal of immunology, Vol. 25, Issue 9, pp. 2718-21, (1995) (PubMed).
Aliases for LAG3 蛋白
lymphocyte activating 3 (LAG3) 蛋白lymphocyte-activation gene 3 (Lag3) 蛋白
lymphocyte activating 3 (Lag3) 蛋白
CD223 蛋白
LAG-3 蛋白
Ly66 蛋白
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