Poliovirus Receptor Protein (PVR) (AA 28-343) (His tag)
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Quick Overview for Poliovirus Receptor Protein (PVR) (AA 28-343) (His tag) (ABIN7274060)
抗原
See all Poliovirus Receptor (PVR) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 28-343
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标记
- This Poliovirus Receptor protein is labelled with His tag.
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原理
- Rhesus macaque CD155/PVR Protein
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序列
- Asp28-Asn343
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产品特性
- Recombinant Rhesus macaque CD155/PVR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp28-Asn343.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Human DNAM-1, hFc Tag captured on CM5 Chip via Protein A can bind Rhesus macaque CD155, His Tag with an affinity constant of 0.234 uM as determined in SPR assay (Biacore T200).,Immobilized Rhesus macaque CD155, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human TIGIT, hFc Tag with the EC50 of 67.6ng/ml determined by ELISA (QC Test).,Rhesus macaque CD155/PVR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Rhesus macaque CD155/PVR is greater than 95% as determined by SEC-HPLC.
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Poliovirus Receptor (PVR) (AA 21-343) (Active) protein (Biotin,His-Avi Tag)
PVR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Poliovirus Receptor (PVR) (AA 29-348) (Active) protein (His tag)PVR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Poliovirus Receptor (PVR) (AA 21-343) (Active) protein (His-Avi Tag)PVR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Poliovirus Receptor (PVR) (AA 21-343) protein (Fc Tag,Biotin)PVR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Poliovirus Receptor (PVR) (AA 21-343) protein (His tag,mFc Tag)PVR 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, AM, ADA
Poliovirus Receptor (PVR) (AA 21-343) protein (Fc Tag)PVR 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, AM, ADA
Poliovirus Receptor (PVR) (AA 21-343) (Active) protein (Fc Tag)PVR 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
Poliovirus Receptor (PVR) (AA 28-343) (Active) protein (His tag)PVR 宿主: 猕猴 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Poliovirus Receptor (PVR) (AA 21-343) (Active) protein (Fc Tag,AVI tag,Biotin)PVR 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Poliovirus Receptor (PVR) (AA 21-343) (Active) protein (His tag,AVI tag,Biotin)PVR 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
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缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- Poliovirus Receptor (PVR)
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别名
- CD155
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背景
- CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the "poliovirus receptor," or PVR.
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分子量
- 35.5 kDa. Due to glycosylation, the protein migrates to 46-60 kDa based on Bis-Tris PAGE result.
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UniProt
- Q0MSE6
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
抗原
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