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Poliovirus Receptor Protein (PVR) (AA 21-343) (His tag,AVI tag,Biotin)

This Recombinant Poliovirus Receptor protein is expressed in HEK-293 Cells.
产品编号 ABIN6386413
发货至: 中国
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Quick Overview for Poliovirus Receptor Protein (PVR) (AA 21-343) (His tag,AVI tag,Biotin) (ABIN6386413)

抗原

See all Poliovirus Receptor (PVR) 蛋白
Poliovirus Receptor (PVR)

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

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HEK-293 Cells

纯度

>95 % as determined by SDS-PAGE.
  • 产品特性

    AA 21-343

    标记

    This Poliovirus Receptor protein is labelled with His tag,AVI tag,Biotin.

    序列

    AA 21-343

    特异性

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

    内毒素水平

    Less than 1.0 EU per μg by the LAL method.
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  • 说明

    Ready-to-use AvitagTM biotinylated protein:
    The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    PBS, pH 7.4

    注意事项

    Please avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C
  • 抗原

    Poliovirus Receptor (PVR)

    别名

    CD155

    背景

    CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that is encoded by the PVR gene. CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses. Subsequent data has also suggested that CD155 may also be used to positively select MHC-independent T cells in the thymus.

    分子量

    38.8 kDa

    NCBI登录号

    NP_006496

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
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