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Poliovirus Receptor Protein (PVR) (AA 21-343) (His-Avi Tag,Biotin)

PVR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274081
发货至: 中国
  • 抗原 See all Poliovirus Receptor (PVR) 蛋白
    Poliovirus Receptor (PVR)
    蛋白类型
    Recombinant
    产品特性
    AA 21-343
    宿主
    • 25
    • 9
    • 3
    • 2
    • 1
    资源
    • 27
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This Poliovirus Receptor protein is labelled with His-Avi Tag,Biotin.
    原理
    Biotinylated Human CD155/PVR Protein
    序列
    Trp21-Asn343
    产品特性
    Recombinant Biotinylated Human CD155/PVR Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Trp21-Asn343.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Biotinylated Human CD155, His Tag at 1μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Human TIGIT, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA. See testing image for detail.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Poliovirus Receptor (PVR)
    别名
    CD155 (PVR 产品)
    别名
    PVR Protein, CD155 Protein, HVED Protein, NECL5 Protein, Necl-5 Protein, PVS Protein, TAGE4 Protein, 3830421F03Rik Protein, D7Ertd458e Protein, Taa1 Protein, Tage4 Protein, mE4 Protein, necl-5 Protein, poliovirus receptor Protein, PVR Protein, Pvr Protein
    背景
    CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the "poliovirus receptor," or PVR.
    分子量
    38 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
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