电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Poliovirus Receptor Protein (PVR) (AA 1-345) (His tag)

PVR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
产品编号 ABIN7320344
发货至: 中国
  • 抗原 See all Poliovirus Receptor (PVR) 蛋白
    Poliovirus Receptor (PVR)
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 1-345
    宿主
    • 26
    • 8
    • 3
    • 2
    • 1
    小鼠
    资源
    • 27
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This Poliovirus Receptor protein is labelled with His tag.
    原理
    Recombinant Mouse CD155/PVR Protein (aa 1-345, His Tag)(Active)
    序列
    Met 1-Arg 345
    产品特性
    A DNA sequence encoding the mouse CD155 (NP_081790.1) precursor (Met 1-Arg 345) was expressed with a C-terminal polyhistidine tag.
    纯度
    > 97 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Biological Activity Comment
    Measured by its ability to bind recombinant mouse CD226/DNAM-1.Immobilized recombinant mouse CD155/PVR at 1 μg/ml (100 μl/well) can bind recombinant mouse CD226/DNAM-1 with a linear range of 0.78-100 ng/ml.
    Top Product
    Discover our top product PVR 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Poliovirus Receptor (PVR)
    别名
    CD155/PVR (PVR 产品)
    别名
    PVR Protein, CD155 Protein, HVED Protein, NECL5 Protein, Necl-5 Protein, PVS Protein, TAGE4 Protein, 3830421F03Rik Protein, D7Ertd458e Protein, Taa1 Protein, Tage4 Protein, mE4 Protein, necl-5 Protein, poliovirus receptor Protein, PVR Protein, Pvr Protein
    背景

    Background: CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhension, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.Immune CheckpointImmune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: ICC Antibodies   Immune Checkpoint Detection: IP Antibodies   Immune Checkpoint Detection: FCM Antibodies   Immune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint Targets   Co-inhibitory Immune Checkpoint Targets Immunotherapy   Cancer Immunotherapy   Targeted Therapy

    Synonym: Poliovirus receptor; CD155 antigen; Nectin-like protein 5; Nectin-2; Tage4 receptor; Pvr; PVR; Necl5; CD155;3830421F03Rik;D7Ertd458e;HVED;mE4;necl-5;PVS;Taa1;Tage4

    分子量
    28 kDa
    NCBI登录号
    NP_081790
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
You are here: