LAG3 Protein (AA 23-450) (Fc Tag,AVI tag,Biotin)
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- 抗原 See all LAG3 蛋白
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 23-450
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This LAG3 protein is labelled with Fc Tag,AVI tag,Biotin.
- 序列
- AA 23-450
- 特异性
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product LAG3 蛋白
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- 说明
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Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
- 别名
- LAG-3 (LAG3 产品)
- 别名
- CD223 Protein, LAG-3 Protein, Ly66 Protein, lymphocyte activating 3 Protein, lymphocyte-activation gene 3 Protein, LAG3 Protein, Lag3 Protein
- 背景
- Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.
- 分子量
- 75.4 kDa
- NCBI登录号
- NP_002277
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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