LAG3 Protein (Fc Tag)
-
- 抗原 See all LAG3 蛋白
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
- 蛋白类型
- Recombinant
-
宿主
- Cynomolgus
-
资源
- 人细胞
- 标记
- This LAG3 protein is labelled with Fc Tag.
- 原理
- Recombinant Cynomolgus LAG-3/CD223 Protein (Fc Tag)
- 序列
- Ala18-His449(Pro74)
- 产品特性
- Recombinant Cynomolgus LAG-3 Protein is produced by our Mammalian expression system and the target gene encoding Ala18-His449(Pro74) is expressed with a Fc tag at the C-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product LAG3 蛋白
-
Lymphocyte-Activation Gene 3 (LAG3) (AA 23-434) protein (His tag)
LAG3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Lymphocyte-Activation Gene 3 (LAG3) (AA 23-450) protein (Fc Tag)LAG3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Lymphocyte-Activation Gene 3 (LAG3) (AA 23-434) protein (His-Avi Tag,Biotin)LAG3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Lymphocyte-Activation Gene 3 (LAG3) protein (His tag)LAG3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE
Lymphocyte-Activation Gene 3 (LAG3) (AA 18-449) (Active) protein (Fc Tag)LAG3 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Lymphocyte-Activation Gene 3 (LAG3) (AA 23-450) (Active) protein (His tag)LAG3 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Lymphocyte-Activation Gene 3 (LAG3) (Active) protein (His tag)LAG3 宿主: Cynomolgus 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Lymphocyte-Activation Gene 3 (LAG3) (AA 23-222) protein (His-IF2DI Tag)LAG3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Lymphocyte-Activation Gene 3 (LAG3) (Active) protein (His tag)LAG3 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE Active
Lymphocyte-Activation Gene 3 (LAG3) (AA 1-360) protein (GST tag)LAG3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution ofPBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
- 别名
- LAG-3/CD223 (LAG3 产品)
- 别名
- CD223 Protein, LAG-3 Protein, Ly66 Protein, lymphocyte activating 3 Protein, lymphocyte-activation gene 3 Protein, LAG3 Protein, Lag3 Protein
- 背景
-
Background: Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. LAG3 is involved in lymphocyte activation and can bind to HLA class-II antigens. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells and acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signaling. It can lead to increased antigen-specific T-cell responses in vivo. LAG-3 has higher affinity to MHC class II than CD4.
Synonym: Lymphocyte activation gene 3 protein,LAG3,LAG-3,Protein FDC,CD223
- 分子量
- 73.6 kDa
- NCBI登录号
- XP_005570011
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
-
