LAG3 Protein (AA 18-449) (Fc Tag)
(1 reference)-
- 抗原 See all LAG3 蛋白
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 18-449
-
宿主
- Cynomolgus
-
资源
- HEK-293 Cells
- 标记
- This LAG3 protein is labelled with Fc Tag.
- 序列
- AA 18-449
- 产品特性
- This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 73.7 kDa. The protein migrates as 78-92 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product LAG3 蛋白
-
Lymphocyte-Activation Gene 3 (LAG3) (AA 23-434) protein (His tag)
LAG3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Lymphocyte-Activation Gene 3 (LAG3) (AA 23-450) protein (Fc Tag)LAG3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Lymphocyte-Activation Gene 3 (LAG3) (AA 23-434) protein (His-Avi Tag,Biotin)LAG3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Lymphocyte-Activation Gene 3 (LAG3) protein (His tag)LAG3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE
Lymphocyte-Activation Gene 3 (LAG3) (AA 23-450) (Active) protein (His tag)LAG3 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Lymphocyte-Activation Gene 3 (LAG3) (Active) protein (His tag)LAG3 宿主: Cynomolgus 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Lymphocyte-Activation Gene 3 (LAG3) (AA 23-222) protein (His-IF2DI Tag)LAG3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Lymphocyte-Activation Gene 3 (LAG3) (Active) protein (His tag)LAG3 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE Active
Lymphocyte-Activation Gene 3 (LAG3) protein (Fc Tag)LAG3 宿主: Cynomolgus 宿主: 人细胞 Recombinant > 90 % as determined by reducing SDS-PAGE.
Lymphocyte-Activation Gene 3 (LAG3) (AA 1-360) protein (GST tag)LAG3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
-
-
: "Characterization of a novel anti-human lymphocyte activation gene 3 (LAG-3) antibody for cancer immunotherapy." in: mAbs, Vol. 11, Issue 6, pp. 1139-1148, (2019) (PubMed).
-
: "Characterization of a novel anti-human lymphocyte activation gene 3 (LAG-3) antibody for cancer immunotherapy." in: mAbs, Vol. 11, Issue 6, pp. 1139-1148, (2019) (PubMed).
-
- 抗原
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
- 别名
- LAG-3 (LAG3 产品)
- 别名
- CD223 Protein, LAG-3 Protein, Ly66 Protein, lymphocyte activating 3 Protein, lymphocyte-activation gene 3 Protein, LAG3 Protein, Lag3 Protein
- 背景
- Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.
- 分子量
- 73.5 kDa
- NCBI登录号
- XP_005570011
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
-
