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NFKB1 抗体 (pThr931) (PE)

NFKB1 适用: 人, 大鼠 FACS 宿主: 兔 Polyclonal PE
产品编号 ABIN6988831
发货至: 中国
  • 抗原 See all NFKB1 抗体
    NFKB1 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))
    抗原表位
    • 35
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    pThr931
    适用
    • 319
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    人, 大鼠
    宿主
    • 316
    • 21
    • 1
    • 1
    克隆类型
    • 311
    • 28
    多克隆
    标记
    • 140
    • 21
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    • 12
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    This NFKB1 antibody is conjugated to PE
    应用范围
    • 179
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    Flow Cytometry (FACS)
    交叉反应
    人, 大鼠
    预测反应
    Mouse,Dog,Cow,Pig,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated Synthesised phosphopeptide derived from human NF KappaB p105 around the phosphorylation site of Thr931
    亚型
    IgG
    Top Product
    Discover our top product NFKB1 Primary Antibody
  • 应用备注
    FCM 1:20-100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    NFKB1 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))
    别名
    NFKB1 (NFKB1 产品)
    别名
    GKLP antibody, NKTL antibody, NTKL antibody, P105 antibody, TAPK antibody, TEIF antibody, TRAP antibody, EBP-1 antibody, KBF1 antibody, NF-kB1 antibody, NF-kappa-B antibody, NF-kappaB antibody, NFKB-p105 antibody, NFKB-p50 antibody, NFkappaB antibody, p105 antibody, p50 antibody, NF-kB antibody, NF-KB1 antibody, ebp-1 antibody, kbf1 antibody, nf-kappa-b antibody, nf-kappaB antibody, nfkb-p105 antibody, nfkb-p50 antibody, NF-kappaB1 antibody, p50/p105 antibody, BICDR-1 antibody, bicdr1 antibody, ccdc64 antibody, SCY1 like pseudokinase 1 antibody, nuclear factor kappa B subunit 1 antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 L homeolog antibody, nuclear factor NF-kappa-B p105 subunit antibody, nucleoporin 107 antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 antibody, SCYL1 antibody, NFKB1 antibody, Nfkb1 antibody, nfkb1.L antibody, CpipJ_CPIJ012236 antibody, Nup107 antibody, nfkb1 antibody
    背景

    Synonyms: NFKB1(phospho T931), NFKB1(phospho Thr931), NF kappa B, NFKB 1, NFKB p105, NFKB p50, NFKB1, Nuclear factor kappa B DNA binding subunit, Nuclear factor NF kappa B p105 subunit, Nuclear factor NF kappa B p50 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B cells 1, DKFZp686C01211, DNA binding factor KBF1, DNA binding factor KBF1 EBP1, EBP 1, EBP1, KBF1, MGC54151, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, Nfkb1, NF-kappaB, NF-kappaB1, NF-KB1, p105, p50, p50/p105, DKFZp686C01211, EBP-1, KBF1, MGC54151, Nf kappa b DNA binding subunit, NF-KAPPAB, NF-KAPPAB1, NFKB, NFKB SUBUNIT P105/P50, NFKB-p105, NFKB1, NUCLEAR FACTOR KAPPA B DNA BINDING SUBUNIT, p105 Nfkb,p50 NF-kappa B,p50NFKB.

    Background: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. SUBUNIT: Active NF-kappa-B is a heterodimer of an about 50 kDa DNA-binding subunit and the weak DNA-binding subunit p65. Two heterodimers might form a labile tetramer. Also interacts with MAP3K8. NF-kappa-B p50 subunit interacts with NCOA3 coactivator, which may coactivate NF-kappa-B dependent expression via its histone acetyltransferase activity. Interacts with DSIPI, this interaction prevents nuclear translocation and DNA-binding. Interacts with SPAG9 and UNC5CL.

    基因ID
    4790
    UniProt
    P19838
    途径
    p53 Pathway, NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, S100 Proteins
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